Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 5/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.30 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18412857 | 0.77 | ALDH1A1 (0.48) | KDM4EPOLBNPSR1ALDH1A1LMNA | |
| SCHEMBL18395227 | 0.76 | KDM4E (0.45) | KDM4EPOLBNPSR1ALDH1A1PRKDC | |
| SCHEMBL20867101 | 0.73 | ALDH1A1 (0.56) | KDM4EPOLBNPSR1ALDH1A1LMNA | |
| SCHEMBL20866838 | 0.68 | ATM (0.32) | KDM4EALDH1A1LMNAAOC3MAPT | |
| SCHEMBL20867306 | 0.67 | ATM (0.31) | LMNAAOC3 | |
| SCHEMBL20369884 | 0.67 | ALDH1A1 (0.57) | KDM4EPOLBALDH1A1LMNAHSD17B10 | |
| SCHEMBL20867213 | 0.66 | KCNH2 (0.40) | KDM4ENPSR1HSD17B10AOC3HPGD | |
| SCHEMBL20866886 | 0.65 | PRKDC (0.45) | LMNAPRKDCMEN1KMT2AMAPT | |
| SCHEMBL20867295 | 0.65 | — | — | |
| SCHEMBL24612210 | 0.63 | FBP1 (0.31) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019067864-A1 | COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-04-04 | — | — | WO | disclosed |