Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10375705 | 0.81 | CYP2D6 (0.53) | ALDH1A1CYP2D6SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL24612153 | 0.81 | ADH1B (0.33) | — | |
| SCHEMBL21863420 | 0.81 | GLO1 (0.43) | ALDH1A1CYP2D6SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL28118734 | 0.79 | CYP2D6 (0.46) | ALDH1A1CYP2D6SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL20867083 | 0.79 | CYP2D6 (0.54) | ALDH1A1CYP2D6SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL20866978 | 0.77 | ALDH1A1 (0.44) | ALDH1A1NPSR1THRBATML3MBTL1 | |
| SCHEMBL20867250 | 0.77 | ALDH1A1 (0.46) | ALDH1A1CYP2D6SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL24612160 | 0.77 | ADH1B (0.38) | SMN1; SMN2GAANPC1 | |
| SCHEMBL21024972 | 0.77 | CYP2D6 (0.47) | ALDH1A1CYP2D6SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL20867220 | 0.76 | CYP2D6 (0.44) | ALDH1A1CYP2D6SMN1; SMN2NPSR1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019067864-A1 | COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-04-04 | — | — | WO | disclosed |