Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 2/20 | 0.33 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31303160 | 0.88 | ADRB2 (0.42) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL25976079 | 0.88 | ADRB2 (0.42) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL31303155 | 0.86 | ADRB2 (0.44) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL25976031 | 0.86 | ADRB2 (0.44) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL2500618 | 0.86 | ADRB2 (0.44) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL20640607 | 0.82 | ADRB2 (0.38) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL31257320 | 0.82 | ADRB2 (0.38) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL20854975 | 0.82 | CYP2D6 (0.38) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL18783308 | 0.81 | ADRB2 (0.38) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL28305984 | 0.78 | ADRB2 (0.36) | ADRB2ADRB1CYP2D6NFKB1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975095-B2 | — | — | 2021-04-13 | — | — | US | disclosed |
| US-20190100530-A1 | BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2019-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190100530-A1 | BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF | HSD17B7, CYP11B1, CYP11B2 | ADRB2 392/4885ADRB1 346/4885CYP2D6 77/4885 |
| US-10975095-B2 | — | CYP1B1, UGT1A1, CYP4B1 | ADRB2 151/4885ADRB1 135/4885CYP2D6 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.