Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 7/20 | 0.40 |
| ▸ | MAOA | P21397 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28601145 | 0.81 | LMNA (0.47) | TP53LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL16874691 | 0.77 | MAOB (0.52) | TP53LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL16874554 | 0.77 | MAOB (0.52) | TP53LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL16874553 | 0.77 | MAOB (0.52) | TP53LMNACYP1A2PTGS1SLC6A2 | |
| Ammonia Solution, Strong SCHEMBL28835126 | 0.76 | MAOB (0.51) | TP53LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL16874764 | 0.74 | TP53 (0.46) | TP53LMNAKCNH2MAOBMAOA | |
| SCHEMBL27954208 | 0.74 | LMNA (0.51) | TP53LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL28103942 | 0.72 | NPC1 (0.47) | TP53LMNARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL20869229 | 0.72 | MAOB (0.45) | TP53LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL20869226 | 0.71 | MAOA (0.48) | LMNACYP1A2PTGS1SLC6A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3688118-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2021-05-19 | — | — | EP | disclosed |
| US-20200263091-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2020-08-20 | — | — | US | disclosed |
| WO-2019063585-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2019-04-04 | — | — | WO | disclosed |