Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | MET | P08581 | 3/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20869380 | 0.87 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNASMN1; SMN2CYP3A4 | |
| SCHEMBL21881839 | 0.82 | KDM4E (0.64) | ALDH1A1KDM4EPPARGPPARAMEN1 | |
| SCHEMBL22295335 | 0.81 | ALDH1A1 (0.51) | ALDH1A1LMNASMN1; SMN2CYP3A4PABPC1 | |
| SCHEMBL534454 | 0.78 | ALDH1A1 (0.56) | ALDH1A1LMNASMN1; SMN2CYP3A4PABPC1 | |
| Quinoline SCHEMBL5148040 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNASMN1; SMN2PABPC1 | |
| SCHEMBL535594 | 0.77 | ALDH1A1 (0.54) | ALDH1A1LMNASMN1; SMN2CYP3A4PPARG | |
| SCHEMBL22386631 | 0.77 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNASMN1; SMN2CYP3A4 | |
| SCHEMBL5267380 | 0.76 | ALDH1A1 (0.68) | ALDH1A1KDM4ELMNASMN1; SMN2CYP3A4 | |
| SCHEMBL4951421 | 0.76 | ALDH1A1 (0.53) | ALDH1A1LMNASMN1; SMN2CYP3A4PPARG | |
| SCHEMBL2494747 | 0.75 | ALDH1A1 (0.72) | ALDH1A1CYP3A4PABPC1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200275661-A1 | QUINOLINE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE | NIPPON SODA CO., LTD. (JP) | 2020-09-03 | — | — | US | disclosed |
| US-20200275661-A1 | QUINOLINE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE | NIPPON SODA CO., LTD. (JP) | 2020-09-03 | — | — | US | disclosed |
| EP-3689866-A1 | QUINOLINE COMPOUND, AND BACTERICIDAL AGENT FOR AGRICULTURAL AND HORTICULTURAL USE | Nippon Soda Co., Ltd. (JP) | 2020-08-05 | — | — | EP | disclosed |
| WO-2019065516-A1 | QUINOLINE COMPOUND, AND BACTERICIDAL AGENT FOR AGRICULTURAL AND HORTICULTURAL USE | 日本曹達株式会社 | 2019-04-04 | — | — | WO | disclosed |
| WO-2019065516-A1 | QUINOLINE COMPOUND, AND BACTERICIDAL AGENT FOR AGRICULTURAL AND HORTICULTURAL USE | 日本曹達株式会社 | 2019-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200275661-A1 | QUINOLINE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE | CBR3, CNPY2, CYP1A2 | ALDH1A1 1883/4885KDM4E 2445/4885LMNA 3912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.