Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 5/20 | 0.53 |
| ▸ | PPARA | Q07869 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 3/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | MST1R | Q04912 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4954671 | 0.87 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2PPARGPPARALMNA | |
| SCHEMBL4951421 | 0.83 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2PPARGPPARALMNA | |
| SCHEMBL8935913 | 0.81 | PPARG (0.77) | ALDH1A1SMN1; SMN2PPARGPPARARAB9A | |
| SCHEMBL8935921 | 0.81 | PPARG (0.77) | ALDH1A1SMN1; SMN2PPARGPPARARAB9A | |
| SCHEMBL30559867 | 0.81 | PPARG (0.77) | ALDH1A1SMN1; SMN2PPARGPPARARAB9A | |
| SCHEMBL534454 | 0.80 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2PPARGPPARALMNA | |
| SCHEMBL535361 | 0.79 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2PPARGPPARALMNA | |
| SCHEMBL3607774 | 0.79 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2PPARGPPARALMNA | |
| SCHEMBL4951418 | 0.78 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2PPARGPPARALMNA | |
| SCHEMBL5118518 | 0.77 | ALOX5 (0.55) | ALDH1A1SMN1; SMN2PPARGPPARALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507509-B2 | Saturated and insaturated bi- or tricyclic aryloxyacetamine derivatives and their use as fungicides | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-13 | — | — | US | disclosed |
| EP-2185518-B1 | Aryloxyacetamide derivatives and their use as fungicides | SYNGENTA PARTICIPATIONS AG (CH) | 2012-02-08 | — | — | EP | disclosed |
| US-20100298356-A1 | SATURATED AND INSATURATED BI- OR TRICYCLIC ARYLOXYACETAMINE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-25 | — | — | US | disclosed |
| EP-2185518-A2 | SATURATED AND INSATURATED BI- OR TRICYCLIC ARYLOXYACETAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | Syngenta Participations AG (CH) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009030467-A2 | SATURATED AND INSATURATED BI- OR TRICYCLIC ARYLOXYACETAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG, (CH) | 2009-03-12 | — | — | WO | disclosed |
| US-7371764-B2 | Quinolin-isoquinolin-and quinazolin-oxyalkylamides and their use as fungicides | SYNGENTA LIMITED (GB) | 2008-05-13 | — | — | US | disclosed |
| CN-100347160-C | Quinolin-, isoquinolin-, and quinazolin-oxyalkylamides and their use as fungicides | SYNGENTA LTD (GB) | 2007-11-07 | — | — | CN | disclosed |
| EP-1567010-B1 | QUINOLIN-, ISOQUINOLIN-, AND QUINAZOLIN-OXYALKYLAMIDES AND THEIR USE AS FUNGICIDES | SYNGENTA LTD (GB) | 2007-10-24 | — | — | EP | disclosed |
| US-20070072884-A1 | QUINOLIN-ISOQUINOLIN-AND QUINAZOLIN-OXYALKYLAMIDES AND THEIR USE AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2007-03-29 | — | — | US | disclosed |
| US-7122672-B2 | Quinolin-, isoquinolin-, and quinazolin-oxyalkylamides and their use as fungicides | SYNGENTA LIMITED (GB) | 2006-10-17 | — | — | US | disclosed |
| US-20060019973-A1 | Quinolin-,isoquinolin-,and quinazolin-oxyalkylamides and their use as fungicides | SYNGENTA LIMITED (GB) | 2006-01-26 | — | — | US | disclosed |
| CN-1717175-A | Quinolin-, isoquinolin-, and quinazolin-oxyalkylamides and their use as fungicides | SYNGENTA LTD (GB) | 2006-01-04 | — | — | CN | disclosed |
| EP-1567010-A1 | QUINOLIN-, ISOQUINOLIN-, AND QUINAZOLIN-OXYALKYLAMIDES AND THEIR USE AS FUNGICIDES | Syngenta Limited (GB) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004047538-A1 | QUINOLIN-, ISOQUINOLIN-, AND QUINAZOLIN-OXYALKYLAMIDES AND THEIR USE AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298356-A1 | SATURATED AND INSATURATED BI- OR TRICYCLIC ARYLOXYACETAMINE DERIVATIVES AND THEIR USE AS FUNGICIDES | CYP1A2, CYP1B1, CYP1A1 | ALDH1A1 109/4885SMN1; SMN2 2208/4885PPARG 323/4885 |
| US-20070072884-A1 | QUINOLIN-ISOQUINOLIN-AND QUINAZOLIN-OXYALKYLAMIDES AND THEIR USE AS FUNGICIDES | CBR3, CBR1, POR | ALDH1A1 2830/4885SMN1; SMN2 4367/4885PPARG 3473/4885 |
| US-20060019973-A1 | Quinolin-,isoquinolin-,and quinazolin-oxyalkylamides and their use as fungicides | CYP4X1, CYP51A1, CYP1A2 | ALDH1A1 896/4885SMN1; SMN2 4038/4885PPARG 3117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.