SCHEMBL20869490

SCHEMBL20869490

CN1CCc2c(ccc(O)c2O)C1

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 5/20 0.49
DRD1 P21728 5/20 0.49
DRD5 P21918 5/20 0.49
DRD3 P35462 4/20 0.49
DRD4 P21917 1/20 0.49
MAOA P21397 3/20 0.47
MAOB P27338 2/20 0.47
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL20854709 0.98 DRD2 (0.48) DRD2DRD1DRD5DRD3DRD4
SCHEMBL20869491 0.85 DRD2 (0.54) DRD2DRD1DRD5DRD3DRD4
SCHEMBL470075 0.78 DRD2 (0.65) DRD2DRD1DRD5DRD3DRD4
Bromide SCHEMBL11819645 0.77 DRD2 (0.55) DRD2DRD1DRD5DRD3DRD4
Bromide SCHEMBL11817641 0.75 DRD1 (0.58) DRD2DRD1DRD5DRD3DRD4
SCHEMBL17607348 0.74 RAC1 (0.38) MAPT
SCHEMBL17462481 0.72 DRD2 (0.51) DRD2DRD1DRD5DRD3DRD4
SCHEMBL7271975 0.71 EGFR (0.42) DRD2DRD1MAPT
SCHEMBL6783570 0.70 MAOA (0.47) DRD2DRD1DRD5DRD3DRD4
SCHEMBL17815299 0.70 MAOA (0.49) DRD2DRD1DRD5DRD3DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019070973-A1 CEPHEM COMPOUNDS WITH LATENT REACTIVE GROUPS GLADIUS PHARMACEUTICALS CORPORATION (CA) 2019-04-11 WO disclosed
US-20190100534-A1 Cephem Compounds with Latent Reactive Groups GLADIUS PHARMACEUTICALS INC (CA) 2019-04-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190100534-A1 Cephem Compounds with Latent Reactive Groups PGLS, GNE, COMT DRD2 1186/4885DRD1 2003/4885DRD5 4048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.