Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20870201 | 0.84 | RORC (0.46) | RORCSCN9AXDHIRAK4BRD4 | |
| SCHEMBL20870215 | 0.83 | RORC (0.45) | RORCSCN9AXDHIRAK4BRD4 | |
| SCHEMBL22297975 | 0.83 | RORC (0.54) | RORCSCN9ABRD4 | |
| SCHEMBL20870409 | 0.83 | RORC (0.49) | RORCSCN9AXDHBRD4 | |
| SCHEMBL28715124 | 0.82 | BRD4 (0.45) | RORCSCN9AXDHBRD4P2RX4 | |
| SCHEMBL20870218 | 0.81 | RORC (0.46) | RORCSCN9AXDHIRAK4BRD4 | |
| SCHEMBL22262327 | 0.80 | ALDH1A1 (0.52) | SCN9ABRD4 | |
| SCHEMBL20529251 | 0.80 | RORC (0.51) | RORCSCN9AP2RX4 | |
| SCHEMBL20870210 | 0.80 | RORC (0.51) | RORCSCN9AP2RX4 | |
| SCHEMBL28715152 | 0.80 | BRD4 (0.43) | RORCSCN9AXDHBRD4OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019063015-A1 | SULFONYL-SUBSTITUTED BICYCLIC COMPOUND WHICH ACTS AS RORγ INHIBITOR | 正大天晴药业集团股份有限公司 | 2019-04-04 | — | — | WO | disclosed |