SCHEMBL208710

SCHEMBL208710

O=CN1CC(O)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL28955876 0.94
SCHEMBL28600951 0.88 ATM (0.31)
SCHEMBL18744921 0.82
Trifluoroacetic Acid SCHEMBL28528335 0.82 ALDH1A1 (0.33)
SCHEMBL16708769 0.81
SCHEMBL1938746 0.81
SCHEMBL28584473 0.81
SCHEMBL765487 0.78
SCHEMBL1307795 0.78
SCHEMBL209084 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658656-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES Beone Medicines I GmbH (CH) 2025-12-10 EP claimed
US-20250346597-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEONE MEDICINES I GMBH (CH) 2025-11-13 US claimed
CN-119790069-A Combinations of Gremlin-1 antagonists and inhibitors of Ras-Raf-MEK-ERK signaling UCB生物制药有限责任公司 2025-04-08 CN claimed
WO-2024160276-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEIGENE, LTD. (KY) 2024-08-08 WO claimed
CN-118290402-A Aminopyrazine diol compounds as PI 3K-gamma inhibitors 因赛特公司 2024-07-05 CN claimed
US-12018021-B2 Thiophene derivatives for the treatment of disorders caused by IgE UCB Biopharma SRL (BE) 2024-06-25 US claimed
US-12006320-B2 Heterocyclic derivatives as PI3K inhibitors INCYTE CORPORATION (US) 2024-06-11 US claimed
CN-118019742-A Novel benzodiazepine derivatives as GABA Aγ1 PAM 豪夫迈·罗氏有限公司 2024-05-10 CN claimed
CN-117957227-A Pyridodiazepine derivatives as GABA Aγ1 PAM 豪夫迈·罗氏有限公司 2024-04-30 CN claimed
EP-4129994-A1 NOVEL PYRIMIDINE DERIVATIVE, AND COMPOSITION FOR PREVENTING OR TREATING NEURODEGENERATIVE DISEASES AND CANCER, COMPRISING SAME Whan In Pharmaceutical Co., Ltd. (KR) 2023-02-08 EP claimed
WO-2011073277-A1 PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS Kv1.3 MODULATORS EVOTEC AG (DE) 2011-06-23 WO claimed
WO-2011073273-A1 BENZOXAZINE ARYL SULFONAMIDE DERIVATIVES AS KV1.3 MODULATORS EVOTEC AG (DE) 2011-06-23 WO claimed
WO-2011014520-A2 COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY IRM LLC (BM) 2011-02-03 WO claimed
US-7687490-B2 2-thioethenyl substituted carbapenem derivatives MEIJI SEIKA KAISHA, LTD. (JP) 2010-03-30 US claimed
US-20090221547-A1 Immunosuppressant Compounds and Compositions IRM LLC (BM) 2009-09-03 US claimed
CN-101291908-A Immunosuppressant compounds and compositions IRM LLC (BM) 2008-10-22 CN claimed
EP-1917240-A1 IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS IRM LLC (BM) 2008-05-07 EP claimed
EP-1870412-A1 2-THIOETHENYL CARBAPENEM DERIVATIVE MEIJI SEIKA KAISHA LTD. (JP) 2007-12-26 EP claimed
WO-2007024922-A1 IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS IRM LLC (BM) 2007-03-01 WO claimed
US-20070004700-A1 2-Thioethenyl substituted carbapenem derivatives MEIJI SEIKA KAISHA, LTD. (JP) 2007-01-04 US claimed