Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL28528335

O=C(O)C(F)(F)F.O=CN1CC(O)C1

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL28709600 0.83 DPP4 (0.35) ALDH1A1L3MBTL1
SCHEMBL208710 0.82
Trifluoroacetic Acid SCHEMBL28698717 0.82 ALDH1A1 (0.39) ALDH1A1L3MBTL1
Trifluoroacetic Acid SCHEMBL30205296 0.77 ALDH1A1 (0.58) ALDH1A1L3MBTL1
Formic Acid SCHEMBL28955876 0.77
Trifluoroacetic Acid SCHEMBL28709650 0.76 HSD17B10 (0.39) ALDH1A1
Trifluoroacetic Acid SCHEMBL30636582 0.74 HSD17B10 (0.42) ALDH1A1
SCHEMBL28600951 0.72 ATM (0.31)
Trifluoroacetic Acid SCHEMBL29897248 0.71 TSHR (0.37) ALDH1A1L3MBTL1
Trifluoroacetic Acid SCHEMBL20593184 0.69 PKM (0.39) ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290402-A Aminopyrazine diol compounds as PI 3K-gamma inhibitors 因赛特公司 2024-07-05 CN disclosed
CN-112074505-B Aminopyrazine diol compounds as PI 3K-gamma inhibitors 因赛特公司 2024-04-05 CN disclosed
CN-115715292-A 1H-pyrazolo [4,3-g ] isoquinoline and 1H-pyrazolo [4,3-g ] quinoline derivatives as alpha-1-antitrypsin modulators for the treatment of alpha-1-antitrypsin deficiency (AATD) 弗特克斯药品有限公司 2023-02-24 CN disclosed
CN-112074505-A Aminopyrazine diol compounds as PI 3K-gamma inhibitors 因赛特公司 2020-12-11 CN disclosed