⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL208710 | 0.94 | — | — | |
| SCHEMBL28600951 | 0.83 | ATM (0.31) | — | |
| SCHEMBL18744921 | 0.77 | — | — | |
| Trifluoroacetic Acid SCHEMBL28528335 | 0.77 | ALDH1A1 (0.33) | — | |
| SCHEMBL1938746 | 0.77 | — | — | |
| SCHEMBL16708769 | 0.77 | — | — | |
| SCHEMBL28584473 | 0.77 | — | — | |
| SCHEMBL1307795 | 0.74 | — | — | |
| SCHEMBL765487 | 0.74 | — | — | |
| SCHEMBL209084 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110402248-B | Azaindoles as HPK1 inhibitors | 豪夫迈·罗氏有限公司 | 2023-01-06 | — | — | CN | disclosed |