Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 11/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 10/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL731645 | 0.81 | NPC1 (0.62) | NPC1CYP11B2CYP11B1CYP1A2RAB9A | |
| SCHEMBL17449911 | 0.79 | PRKCZ (0.54) | NPC1PRKCZCYP11B2CYP11B1CYP3A4 | |
| SCHEMBL28271036 | 0.78 | NPC1 (0.74) | NPC1CYP1A2RAB9AL3MBTL1KDM4E | |
| SCHEMBL1445233 | 0.78 | MIF (0.50) | PRKCZCYP11B2CYP11B1CYP3A4CYP2D6 | |
| SCHEMBL20873066 | 0.78 | PRKCZ (0.64) | PRKCZCYP11B2CYP11B1CYP3A4CYP2D6 | |
| SCHEMBL12676858 | 0.76 | CYP11B2 (0.51) | NPC1PRKCZCYP11B2CYP11B1CYP3A4 | |
| SCHEMBL12386965 | 0.76 | CYP11B2 (0.51) | PRKCZCYP11B2CYP11B1CYP3A4CYP2D6 | |
| SCHEMBL12428417 | 0.76 | CYP11B2 (0.51) | PRKCZCYP11B2CYP11B1CYP3A4CYP2D6 | |
| SCHEMBL2300302 | 0.76 | CYP11B2 (0.51) | PRKCZCYP11B2CYP11B1CYP3A4CYP2D6 | |
| SCHEMBL5470573 | 0.76 | NPC1 (0.63) | NPC1CYP1A2RAB9AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3466932-A1 | PRODUCTION METHOD FOR BICYCLIC NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | Kobelco Eco-Solutions Co., Ltd (JP) | 2019-04-10 | — | — | EP | disclosed |