SCHEMBL2300302

SCHEMBL2300302

Brc1ccc(-c2cncc3ccccc23)nc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP11B2 P19099 13/20 0.51
▸ CYP11B1 P15538 10/20 0.51
▸ PRKCZ Q05513 1/20 0.46
▸ CNR1 P21554 1/20 0.44
▸ CNR2 P34972 1/20 0.44
▸ IRAK4 Q9NWZ3 1/20 0.39
▸ CYP3A4 P08684 2/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ CYP2D6 P10635 1/20 0.39
▸ CYP2C9 P11712 1/20 0.39
▸ CYP2B6 P20813 1/20 0.39
▸ CYP2C19 P33261 1/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ CYP17A1 P05093 1/20 0.38
▸ SLC22A12 Q96S37 1/20 0.37
▸ HTR2C P28335 1/20 0.37
▸ KCNA5 P22460 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1534980 0.83 CYP11B2 (0.48) CYP11B2CYP11B1MEN1LMNAMAPT
SCHEMBL12428417 0.80 CYP11B2 (0.51) CYP11B2CYP11B1PRKCZCNR1CNR2
SCHEMBL12386965 0.80 CYP11B2 (0.51) CYP11B2CYP11B1PRKCZCNR1CNR2
SCHEMBL12676858 0.77 CYP11B2 (0.51) CYP11B2CYP11B1PRKCZCNR1CNR2
SCHEMBL971084 0.77 PRKCZ (0.69) CYP11B2CYP11B1PRKCZCYP3A4CYP1A2
SCHEMBL38660559 0.77 PRKCZ (0.69) CYP11B2CYP11B1PRKCZCYP3A4CYP1A2
SCHEMBL5085279 0.77 CNR1 (0.53) CYP11B2CYP11B1PRKCZCNR1CNR2
SCHEMBL24871209 0.76 PRKCZ (0.67) CYP11B2CYP11B1PRKCZCYP3A4CYP1A2
SCHEMBL20873080 0.76 NPC1 (0.54) CYP11B2CYP11B1PRKCZCNR1CNR2
SCHEMBL1445121 0.76 CYP11B2 (0.50) CYP11B2CYP11B1PRKCZCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024109660-A1 CDK INHIBITORS 上海齐鲁制药研究中心有限公司 2024-05-30 — — WO disclosed
US-8735577-B2 1,3,5-triazine derivative, process for producing same, and organic electroluminescent element comprising same as constituent component TOSOH CORPORATION (JP) 2014-05-27 — — US disclosed
US-8735577-B2 1,3,5-triazine derivative, process for producing same, and organic electroluminescent element comprising same as constituent component TOSOH CORPORATION (JP) 2014-05-27 — — US disclosed
US-8735577-B2 1,3,5-triazine derivative, process for producing same, and organic electroluminescent element comprising same as constituent component TOSOH CORPORATION (JP) 2014-05-27 — — US disclosed
EP-2351750-B1 1,3,5-TRIAZINE DERIVATIVE, PROCESS FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AS CONSTITUENT TOSOH CORP (JP) 2014-03-12 — — EP disclosed
US-8367219-B2 Anthracene-based compound and organic light emitting device employing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-02-05 — — US disclosed
US-8367220-B2 Anthracene-based compound and organic light emitting device employing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-02-05 — — US disclosed
CN-102239161-A 1,3, 5-triazine derivative, method for producing same, and organic electroluminescent device comprising same as constituent TOSOH CORP 2011-11-09 — — CN disclosed
US-20110190494-A1 1,3,5-TRIAZINE DERIVATIVE, PROCESS FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME AS CONSTITUENT COMPONENT TOSOH CORPORATION (JP) 2011-08-04 — — US disclosed
US-20110190494-A1 1,3,5-TRIAZINE DERIVATIVE, PROCESS FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME AS CONSTITUENT COMPONENT TOSOH CORPORATION (JP) 2011-08-04 — — US disclosed
US-20110190494-A1 1,3,5-TRIAZINE DERIVATIVE, PROCESS FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME AS CONSTITUENT COMPONENT TOSOH CORPORATION (JP) 2011-08-04 — — US disclosed
EP-2351750-A1 1,3,5-TRIAZINE DERIVATIVE, PROCESS FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME AS CONSTITUENT COMPONENT Tosoh Corporation (JP) 2011-08-03 — — EP disclosed
CN-101570536-A Anthracene-based compound and organic light emitting device employing the same SAMSUNG ELECTRONICS CO LTD (KR) 2009-11-04 — — CN disclosed
US-20090166670-A1 Anthracene-based compound and organic light emitting device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2009-07-02 — — US disclosed
EP-2055702-A1 Anthracene-based compound and organic light emitting device employing the same Samsung Electronics Co., Ltd. (KR) 2009-05-06 — — EP disclosed
US-20090108746-A1 Anthracene-based compound and organic light emitting device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2009-04-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110190494-A1 1,3,5-TRIAZINE DERIVATIVE, PROCESS FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME AS CONSTITUENT COMPONENT ASH2L, SETDB1, KAT5 CYP11B2 1254/4885CYP11B1 1323/4885PRKCZ 4761/4885
US-20090166670-A1 Anthracene-based compound and organic light emitting device employing the same CCNL2, CRY2, ATXN2L CYP11B2 1213/4885CYP11B1 1455/4885PRKCZ 4592/4885
US-20090108746-A1 Anthracene-based compound and organic light emitting device employing the same CCNL2, CRY2, ATXN2L CYP11B2 1213/4885CYP11B1 1455/4885PRKCZ 4592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback