Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 3/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 4/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16234662 | 0.88 | KMO (0.46) | HTR2AHTR2CSLC6A2SLC6A4TP53 | |
| SCHEMBL22798770 | 0.88 | SLC6A2 (0.48) | HTR2AHTR2CSLC6A2SLC6A4TP53 | |
| SCHEMBL22798768 | 0.88 | SLC6A2 (0.48) | HTR2AHTR2CSLC6A2SLC6A4TP53 | |
| SCHEMBL22798937 | 0.88 | SLC6A2 (0.48) | HTR2AHTR2CSLC6A2SLC6A4TP53 | |
| SCHEMBL2007680 | 0.86 | HTR2A (0.49) | HTR2AHTR2CSLC6A2SLC6A4TP53 | |
| SCHEMBL13980998 | 0.83 | HTR2A (0.45) | HTR2AHTR2CSLC6A2SLC6A4TP53 | |
| SCHEMBL598834 | 0.80 | HTR2A (0.54) | HTR2AHTR2CSLC6A2SLC6A4TP53 | |
| SCHEMBL20876087 | 0.78 | SLC6A2 (0.50) | HTR2AHTR2CSLC6A2SLC6A4TP53 | |
| SCHEMBL10203775 | 0.77 | NOTUM (0.53) | SLC6A2SLC6A4 | |
| SCHEMBL1576677 | 0.75 | KMO (0.49) | HTR2AHTR2CSLC6A2SLC6A4OXER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11629138-B2 | Microbiocidal picolinamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-04-18 | — | — | US | disclosed |
| EP-3692029-B1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-04-12 | — | — | EP | disclosed |
| CN-111194314-B | Microbicidal pyridine amide derivative | 先正达参股股份有限公司 | 2022-12-30 | — | — | CN | disclosed |
| US-20200255400-A1 | Microbiocidal Picolinamide Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-13 | — | — | US | disclosed |
| US-20200255400-A1 | Microbiocidal Picolinamide Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-13 | — | — | US | disclosed |
| EP-3692029-A1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | Syngenta Participations AG (CH) | 2020-08-12 | — | — | EP | disclosed |
| CN-111194314-A | Microbicidal picolinamide derivatives | 先正达参股股份有限公司 | 2020-05-22 | — | — | CN | disclosed |
| WO-2019068809-A1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-04-11 | — | — | WO | disclosed |
| WO-2019068809-A1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255400-A1 | Microbiocidal Picolinamide Derivatives | PRF1, CASP1, FPR1 | HTR2A 1946/4885HTR2C 2046/4885SLC6A2 3920/4885 |
| US-11629138-B2 | Microbiocidal picolinamide derivatives | PRF1, CASP1, FPR1 | HTR2A 1946/4885HTR2C 2046/4885SLC6A2 3920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.