Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11210348 | 0.87 | CA12 (0.48) | CA12CA1CA9LMNAGAA | |
| SCHEMBL871699 | 0.85 | — | — | |
| SCHEMBL30957353 | 0.85 | CA12 (0.46) | CA12CA1CA9LMNAGAA | |
| SCHEMBL7846668 | 0.85 | CAMK2A (0.41) | CA12CA1CA9CAMK2AMMP1 | |
| SCHEMBL6142653 | 0.84 | CA12 (0.43) | CA12CA1CA9LMNAHPGD | |
| SCHEMBL969160 | 0.83 | CA12 (0.61) | CA12CA1CA9LMNAGAA | |
| SCHEMBL8629998 | 0.81 | CA12 (0.43) | CA12CA1CA9LMNAGAA | |
| Hydrochloric Acid SCHEMBL10823198 | 0.81 | CA12 (0.59) | CA12CA1CA9LMNAGAA | |
| SCHEMBL6247927 | 0.80 | CAMK2A (0.38) | CA12CA1CA9GAACAMK2A | |
| SCHEMBL11595248 | 0.80 | CAMK2A (0.38) | CA12CA1CA9LMNACAMK2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11623922-B2 | Compounds | INFLAZOME LIMITED (IE) | 2023-04-11 | — | — | US | disclosed |
| US-20200331886-A1 | NOVEL COMPOUNDS | INFLAZOME LIMITED (IE) | 2020-10-22 | — | — | US | disclosed |
| EP-3692020-A1 | NOVEL COMPOUNDS | Inflazome Limited (IE) | 2020-08-12 | — | — | EP | disclosed |
| WO-2019068772-A1 | NOVEL COMPOUNDS | INFLAZOME LIMITED (IE) | 2019-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11623922-B2 | Compounds | NLRP3, NOD1, NLRP1 | CA12 3358/4885CA1 2885/4885CA9 1543/4885 |
| US-20200331886-A1 | NOVEL COMPOUNDS | NLRP3, NOD1, NLRP1 | CA12 4034/4885CA1 3582/4885CA9 2599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.