SCHEMBL7846668

SCHEMBL7846668

O=C(O)N(CCCO)CCCO

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CAMK2A Q9UQM7 1/20 0.41
GPR84 Q9NQS5 1/20 0.38
FFAR1 O14842 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38
NTRK2 Q16620 1/20 0.37
HDAC1 Q13547 2/20 0.36
HDAC6 Q9UBN7 2/20 0.36
REN P00797 1/20 0.32
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA9 Q16790 2/20 0.32
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC9 Q9UKV0 1/20 0.31
HDAC5 Q9UQL6 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9230251 0.95 GPR84 (0.40) CAMK2AGPR84FFAR1FFAR4NTRK2
SCHEMBL6247927 0.95 CAMK2A (0.38) CAMK2AGPR84FFAR1FFAR4NTRK2
SCHEMBL11595248 0.89 CAMK2A (0.38) CAMK2AGPR84FFAR1FFAR4NTRK2
SCHEMBL6142653 0.88 CA12 (0.43) CAMK2ANTRK2CA12CA1CA9
SCHEMBL6246329 0.87 GPR84 (0.39) CAMK2AGPR84FFAR1FFAR4NTRK2
SCHEMBL20876137 0.85 CA12 (0.43) CAMK2AGPR84NTRK2HDAC1HDAC6
SCHEMBL6883197 0.83 CA12 (0.35) CAMK2AGPR84FFAR1FFAR4REN
SCHEMBL17841944 0.82 NTRK2 (0.33) CAMK2ANTRK2HDAC1HDAC6
SCHEMBL2493116 0.81 CA12 (0.41) CAMK2AHDAC1HDAC6CA12CA1
SCHEMBL23120358 0.79 ALOX5 (0.53) HDAC1HDAC6RENHDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0797611-B1 ACID ETCH RESISTANT AUTOMOTIVE TOPCOAT KING INDUSTRIES INC (US) 1999-01-27 EP claimed
US-11084779-B2 Cationic lipids for therapeutic agent delivery formulations NITTO DENKO CORPORATION (JP) 2021-08-10 US disclosed
US-10961181-B2 2021-03-30 US disclosed
US-20200199064-A1 CATIONIC LIPIDS FOR THERAPEUTIC AGENT DELIVERY FORMULATIONS NITTO DENKO CORPORATION (JP) 2020-06-25 US disclosed
EP-2998289-B1 COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING SIRNA ACTIVITY NITTO DENKO CORP (JP) 2019-08-07 EP disclosed
US-10196637-B2 Retinoid-lipid drug carrier NITTO DENKO CORPORATION (JP) 2019-02-05 US disclosed
US-20180208547-A1 CATIONIC LIPIDS FOR THERAPEUTIC AGENT DELIVERY FORMULATIONS NITTO DENKO CORPORATION (JP) 2018-07-26 US disclosed
US-9963424-B2 Cationic lipids for therapeutic agent delivery formulations NITTO DENKO CORPORATION (JP) 2018-05-08 US disclosed
US-20170081663-A1 RETINOID-LIPID DRUG CARRIER NITTO DENKO CORPORATION (JP) 2017-03-23 US disclosed
US-20160137593-A1 Cationic Lipids for Therapeutic Agent Delivery Formulations NITTO DENKO CORP (JP) 2016-05-19 US disclosed
EP-1021245-A4 NOVEL ZIRCONIUM URETHANE CATALYSTS KING INDUSTRIES INC (US) 2001-11-14 EP disclosed
EP-1021245-A1 NOVEL ZIRCONIUM URETHANE CATALYSTS KING INDUSTRIES, INC. (US) 2000-07-26 EP disclosed
EP-0797611-B1 ACID ETCH RESISTANT AUTOMOTIVE TOPCOAT KING INDUSTRIES INC (US) 1999-01-27 EP disclosed
WO-1998041322-A1 NOVEL ZIRCONIUM URETHANE CATALYSTS KING INDUSTRIES, INC. (US) 1998-09-24 WO disclosed
EP-0797611-A1 ACID ETCH RESISTANT AUTOMOTIVE TOPCOAT Blank, Werner J. (US) 1997-10-01 EP disclosed
US-5565531-A AUTOMOBILE PROTECTIVE TOPCOATINGS COMPRISING POLYURETHANES HAVING PENDANT ALKYL CHAINS CONTAINING AN ETHER MADE FROM A DICARBAMATE, POLYOL AND ETHER-CONTAINING CARBAMATE; WEATHERPROOFING; DURABILITY; SOLVENT SOLUBILITY KING INDUSTRIES, INC. (US) 1996-10-15 US disclosed
WO-1995032999-A1 ACID ETCH RESISTANT AUTOMOTIVE TOPCOAT BLANK WERNER J (US) 1995-12-07 WO disclosed
US-5336704-A Within hydrogel chelation polymer using precipitative anion; safe disposal of toxic metals RAINER NORMAN B (US) 1994-08-09 US disclosed
EP-0204234-A2 Use of polyesters with sulfonic acid groups Henkel Kommanditgesellschaft auf Aktien (DE) 1986-12-10 EP disclosed
US-4472165-A UREA-FORMALDEHYDE RESIN, WRINKLE RESISTANCE, FOAMING, SCAVENGERS, COLLAPSING, CURING UNITED MERCHANTS AND MANUFACTURERS, INC. (US) 1984-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160137593-A1 Cationic Lipids for Therapeutic Agent Delivery Formulations SGMS1, SGMS2, CERT1 CAMK2A 4568/4885GPR84 872/4885FFAR1 194/4885
US-20180208547-A1 CATIONIC LIPIDS FOR THERAPEUTIC AGENT DELIVERY FORMULATIONS SGMS1, SGMS2, S1PR1 CAMK2A 4204/4885GPR84 836/4885FFAR1 230/4885
US-20200199064-A1 CATIONIC LIPIDS FOR THERAPEUTIC AGENT DELIVERY FORMULATIONS SGMS1, SGMS2, CERT1 CAMK2A 4565/4885GPR84 721/4885FFAR1 177/4885
US-20170081663-A1 RETINOID-LIPID DRUG CARRIER RXRA, RXRG, LRAT CAMK2A 3677/4885GPR84 812/4885FFAR1 869/4885
US-10961181-B2 DEGS1, SGMS1, C5 CAMK2A 4422/4885GPR84 501/4885FFAR1 212/4885
US-11084779-B2 Cationic lipids for therapeutic agent delivery formulations SGMS1, SGMS2, CERT1 CAMK2A 4565/4885GPR84 721/4885FFAR1 177/4885
US-10196637-B2 Retinoid-lipid drug carrier RXRA, RXRG, LRAT CAMK2A 3677/4885GPR84 812/4885FFAR1 869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.