SCHEMBL20876170

SCHEMBL20876170

Cc1nc(N(C)C(=O)Cc2ccc(-c3cc(F)ccc3F)cc2)sc1[S+](C)[O-]

nearest known ligand 0.72

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA12 O43570 18/20 0.72
CA1 P00915 18/20 0.72
CA2 P00918 18/20 0.72
CA5A P35218 18/20 0.72
CA9 Q16790 18/20 0.72
CA5B Q9Y2D0 18/20 0.72
WNT3A P56704 1/20 0.38
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31187475 1.00 CA12 (0.72) CA12CA1CA2CA5ACA9
SCHEMBL29635239 0.94 CA12 (0.66) CA12CA1CA2CA5ACA9
SCHEMBL22294683 0.92 CA12 (0.71) CA12CA1CA2CA5ACA9
SCHEMBL25892249 0.92 CA12 (0.74) CA12CA1CA2CA5ACA9
SCHEMBL19456935 0.91 CA12 (0.62) CA12CA1CA2CA5ACA9
SCHEMBL25854803 0.90 CA12 (0.63) CA12CA1CA2CA5ACA9
SCHEMBL20888597 0.88 CA12 (0.67) CA12CA1CA2CA5ACA9
SCHEMBL28937197 0.86 CA12 (0.72) CA12CA1CA2CA5ACA9
SCHEMBL24767096 0.84 CA12 (0.74) CA12CA1CA2CA5ACA9
SCHEMBL30123365 0.84 CA12 (1.00) CA12CA1CA2CA5ACA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137669-A1 NOVEL ENANTIOMERS OF A SERIES OF ANTIVIRAL COMPOUNDS INNOVATIVE MOLECULES GMBH (DE) 2026-05-21 US disclosed
US-12527778-B2 Enantiomers of a series of antiviral compounds INNOVATIVE MOLECULES GMBH (DE) 2026-01-20 US disclosed
US-12295945-B2 Enantiomers of substituted thiazoles as antiviral compounds INNOVATIVE MOLECULES GMBH (DE) 2025-05-13 US disclosed
US-20240316021-A1 NOVEL ENANTIOMERS OF A SERIES OF ANTIVIRAL COMPOUNDS INNOVATIVE MOLECULES GMBH (DE) 2024-09-26 US disclosed
CN-111433203-B Enantiomer of substituted thiazoles as antiviral compounds 创新分子股份有限公司 2024-02-13 CN disclosed
EP-4209491-A1 ENANTIOMERS OF SUBSTITUTED THIAZOLES AS ANTIVIRAL COMPOUNDS Innovative Molecules GmbH (DE) 2023-07-12 EP disclosed
EP-4209491-A1 ENANTIOMERS OF SUBSTITUTED THIAZOLES AS ANTIVIRAL COMPOUNDS Innovative Molecules GmbH (DE) 2023-07-12 EP disclosed
EP-3692039-B1 ENANTIOMERS OF SUBSTITUTED THIAZOLES AS ANTIVIRAL COMPOUNDS INNOVATIVE MOLECULES GMBH (DE) 2022-12-14 EP disclosed
EP-3692039-B1 ENANTIOMERS OF SUBSTITUTED THIAZOLES AS ANTIVIRAL COMPOUNDS INNOVATIVE MOLECULES GMBH (DE) 2022-12-14 EP disclosed
CN-109071473-B Antiviral compounds 创新分子股份有限公司 2022-12-09 CN disclosed
CN-111433203-A Enantiomers of substituted thiazoles as antiviral compounds 创新分子股份有限公司 2020-07-17 CN disclosed
US-20200148652-A1 Aminothiazole Derivatives Useful As Antiviral Agents INNOVATIVE MOLECULES GMBH (DE) 2020-05-14 US disclosed
US-20200148652-A1 Aminothiazole Derivatives Useful As Antiviral Agents INNOVATIVE MOLECULES GMBH (DE) 2020-05-14 US disclosed
US-10590094-B2 Aminothiazole derivatives useful as antiviral agents INNOVATIVE MOLECULES GMBH (DE) 2020-03-17 US disclosed
US-10590094-B2 Aminothiazole derivatives useful as antiviral agents INNOVATIVE MOLECULES GMBH (DE) 2020-03-17 US disclosed
US-20190112285-A1 Aminothiazole Derivatives Useful As Antiviral Agents INNOVATIVE MOLECULES GMBH (DE) 2019-04-18 US disclosed
US-20190112285-A1 Aminothiazole Derivatives Useful As Antiviral Agents INNOVATIVE MOLECULES GMBH (DE) 2019-04-18 US disclosed
WO-2019068817-A1 ENANTIOMERS OF SUBSTITUTED THIAZOLES AS ANTIVIRAL COMPOUNDS INNOVATIVE MOLECULES GMBH (DE) 2019-04-11 WO disclosed
WO-2019068817-A1 ENANTIOMERS OF SUBSTITUTED THIAZOLES AS ANTIVIRAL COMPOUNDS INNOVATIVE MOLECULES GMBH (DE) 2019-04-11 WO disclosed
CN-109071473-A Novel antivirus compound 创新分子股份有限公司 2018-12-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12295945-B2 Enantiomers of substituted thiazoles as antiviral compounds EIF2AK2, MAVS, ZC3HAV1 CA12 4867/4885CA1 4865/4885CA2 4604/4885
US-20240316021-A1 NOVEL ENANTIOMERS OF A SERIES OF ANTIVIRAL COMPOUNDS EIF2AK2, MAVS, SARS1 CA12 4748/4885CA1 4827/4885CA2 4611/4885
US-20200148652-A1 Aminothiazole Derivatives Useful As Antiviral Agents MAVS, EIF2AK2, SARS1 CA12 4742/4885CA1 4843/4885CA2 4245/4885
US-20190112285-A1 Aminothiazole Derivatives Useful As Antiviral Agents MAVS, EIF2AK2, SARS1 CA12 4770/4885CA1 4844/4885CA2 4253/4885
US-12527778-B2 Enantiomers of a series of antiviral compounds CA2, CA6, HCFC1 CA12 4/4885CA1 6/4885CA2 1/4885
US-20260137669-A1 NOVEL ENANTIOMERS OF A SERIES OF ANTIVIRAL COMPOUNDS IFNAR1, CCR10, EIF2AK2 CA12 2877/4885CA1 4619/4885CA2 3814/4885
US-10590094-B2 Aminothiazole derivatives useful as antiviral agents MAVS, EIF2AK2, SARS1 CA12 4770/4885CA1 4844/4885CA2 4253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.