SCHEMBL20876182

SCHEMBL20876182

Cc1nc(N(C)C(=O)Cc2ccc(-c3cc(F)ccc3F)cc2)sc1[S@@](C)(=N)=O

nearest known ligand 0.83

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA12 O43570 20/20 0.83
CA1 P00915 20/20 0.83
CA2 P00918 20/20 0.83
CA5A P35218 20/20 0.83
CA9 Q16790 20/20 0.83
CA5B Q9Y2D0 20/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31213329 1.00 CA12 (0.83) CA12CA1CA2CA5ACA9
SCHEMBL20876180 1.00 CA12 (0.83) CA12CA1CA2CA5ACA9
SCHEMBL22405737 1.00 CA12 (0.83) CA12CA1CA2CA5ACA9
SCHEMBL31388226 0.94 CA12 (0.73) CA12CA1CA2CA5ACA9
SCHEMBL29635266 0.94 CA12 (0.73) CA12CA1CA2CA5ACA9
SCHEMBL29635247 0.94 CA12 (0.73) CA12CA1CA2CA5ACA9
SCHEMBL20897298 0.92 CA12 (0.88) CA12CA1CA2CA5ACA9
SCHEMBL1177291 0.91 CA12 (1.00) CA12CA1CA2CA5ACA9
SCHEMBL20897307 0.91 CA12 (0.86) CA12CA1CA2CA5ACA9
SCHEMBL30123365 0.91 CA12 (1.00) CA12CA1CA2CA5ACA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137669-A1 NOVEL ENANTIOMERS OF A SERIES OF ANTIVIRAL COMPOUNDS INNOVATIVE MOLECULES GMBH (DE) 2026-05-21 US claimed
US-20250115565-A1 SOLID CRYSTALLINE FORMS OF HELICASE-PRIMASE INHIBITORS AND PROCESS OF PREPARATION THEREOF INNOVATIVE MOLECULES GMBH (DE) 2025-04-10 US claimed
EP-4466255-A1 SOLID CRYSTALLINE FORMS OF HELICASE-PRIMASE INHIBITORS AND PROCESS OF PREPARATION THEREOF Innovative Molecules GmbH (DE) 2024-11-27 EP claimed
US-20240316021-A1 NOVEL ENANTIOMERS OF A SERIES OF ANTIVIRAL COMPOUNDS INNOVATIVE MOLECULES GMBH (DE) 2024-09-26 US claimed
WO-2023135303-A1 SOLID CRYSTALLINE FORMS OF HELICASE-PRIMASE INHIBITORS AND PROCESS OF PREPARATION THEREOF INNOVATIVE MOLECULES GMBH (DE) 2023-07-20 WO claimed
US-11278534-B2 Enantiomers of substituted thiazoles as antiviral compounds Innovative Molecules GmbG (DE) 2022-03-22 US claimed
US-20200289486-A1 Enantiomers Of Substituted Thiazoles As Antiviral Compounds INNOVATIVE MOLECULES GMBH (DE) 2020-09-17 US claimed
EP-3692039-A1 ENANTIOMERS OF SUBSTITUTED THIAZOLES AS ANTIVIRAL COMPOUNDS Innovative Molecules GmbH (DE) 2020-08-12 EP claimed
WO-2019068817-A1 ENANTIOMERS OF SUBSTITUTED THIAZOLES AS ANTIVIRAL COMPOUNDS INNOVATIVE MOLECULES GMBH (DE) 2019-04-11 WO claimed
EP-4747240-A1 MICRONIZED CRYSTALLINE HYDROCHLORIDE SALTS OF ANTIVIRAL HELICASE-PRIMASE INHIBITOR COMPOUNDS Innovative Molecules GmbH (DE) 2026-05-27 EP disclosed
US-20260137669-A1 NOVEL ENANTIOMERS OF A SERIES OF ANTIVIRAL COMPOUNDS INNOVATIVE MOLECULES GMBH (DE) 2026-05-21 US disclosed
US-12527778-B2 Enantiomers of a series of antiviral compounds INNOVATIVE MOLECULES GMBH (DE) 2026-01-20 US disclosed
EP-4580601-A1 PHARMACEUTICAL COMPOSITIONS FOR HERPES VIRUS Assembly Biosciences, Inc. (US) 2025-07-09 EP disclosed
US-12295945-B2 Enantiomers of substituted thiazoles as antiviral compounds INNOVATIVE MOLECULES GMBH (DE) 2025-05-13 US disclosed
US-20210401810-A1 Helicase Primase Inhibitors For Treating Cancer In A Combination Therapy With Oncolytic Viruses INNOVATIVE MOLECULES GMBH (DE) 2021-12-30 US disclosed
US-20200289486-A1 Enantiomers Of Substituted Thiazoles As Antiviral Compounds INNOVATIVE MOLECULES GMBH (DE) 2020-09-17 US disclosed
EP-3692039-A1 ENANTIOMERS OF SUBSTITUTED THIAZOLES AS ANTIVIRAL COMPOUNDS Innovative Molecules GmbH (DE) 2020-08-12 EP disclosed
WO-2020109389-A1 HELICASE PRIMASE INHIBITORS FOR TREATING CANCER IN A COMBINATION THERAPY WITH ONCOLYTIC VIRUSES INNOVATIVE MOLECULES GMBH (DE) 2020-06-04 WO disclosed
WO-2019068817-A1 ENANTIOMERS OF SUBSTITUTED THIAZOLES AS ANTIVIRAL COMPOUNDS INNOVATIVE MOLECULES GMBH (DE) 2019-04-11 WO disclosed
WO-2019068817-A1 ENANTIOMERS OF SUBSTITUTED THIAZOLES AS ANTIVIRAL COMPOUNDS INNOVATIVE MOLECULES GMBH (DE) 2019-04-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12295945-B2 Enantiomers of substituted thiazoles as antiviral compounds EIF2AK2, MAVS, ZC3HAV1 CA12 4867/4885CA1 4865/4885CA2 4604/4885
US-20240316021-A1 NOVEL ENANTIOMERS OF A SERIES OF ANTIVIRAL COMPOUNDS EIF2AK2, MAVS, SARS1 CA12 4748/4885CA1 4827/4885CA2 4611/4885
US-11278534-B2 Enantiomers of substituted thiazoles as antiviral compounds EIF2AK2, MAVS, ZC3HAV1 CA12 4855/4885CA1 4850/4885CA2 4269/4885
US-20210401810-A1 Helicase Primase Inhibitors For Treating Cancer In A Combination Therapy With Oncolytic Viruses DNA2, DDX24, DDX41 CA12 3243/4885CA1 3457/4885CA2 3657/4885
US-20200289486-A1 Enantiomers Of Substituted Thiazoles As Antiviral Compounds EIF2AK2, MAVS, ZC3HAV1 CA12 4855/4885CA1 4850/4885CA2 4269/4885
US-20250115565-A1 SOLID CRYSTALLINE FORMS OF HELICASE-PRIMASE INHIBITORS AND PROCESS OF PREPARATION THEREOF DNA2, RECQL, BLM CA12 3081/4885CA1 1807/4885CA2 2800/4885
US-12527778-B2 Enantiomers of a series of antiviral compounds CA2, CA6, HCFC1 CA12 4/4885CA1 6/4885CA2 1/4885
US-20260137669-A1 NOVEL ENANTIOMERS OF A SERIES OF ANTIVIRAL COMPOUNDS IFNAR1, CCR10, EIF2AK2 CA12 2877/4885CA1 4619/4885CA2 3814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.