Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | YWHAG | P61981 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2088703 | 0.99 | NPC1 (0.38) | NPC1HPGDTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL2090404 | 0.88 | TP53 (0.42) | NPC1HPGDTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL2087120 | 0.87 | TP53 (0.40) | NPC1HPGDTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL474502 | 0.79 | NPC1 (0.44) | NPC1HPGDSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL2087637 | 0.76 | MRGPRX4 (0.36) | HPGDTP53SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL18426844 | 0.73 | NPC1 (0.46) | NPC1HPGDSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL5092225 | 0.72 | NPC1 (0.57) | NPC1SMN1; SMN2ALDH1A1HTTMAPT | |
| SCHEMBL9544174 | 0.71 | ALDH1A1 (0.47) | NPC1HPGDSMN1; SMN2ALDH1A1HTT | |
| Bromide SCHEMBL9763941 | 0.70 | ALDH1A1 (0.46) | NPC1HPGDSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL3052982 | 0.70 | ALDH1A1 (0.43) | NPC1HPGDSMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863450-B2 | Compounds comprising an oxazoline or thiazoline moiety, processes for making them, and their uses | UCB PHARMA, S.A. (BE) | 2011-01-04 | — | — | US | disclosed |
| US-20080161331-A1 | Compounds Comprising an Oxazoline or Thiazoline Moiety, Processes for Making Them, and Their Uses | UCB PHARMA, S.A. (BE) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161331-A1 | Compounds Comprising an Oxazoline or Thiazoline Moiety, Processes for Making Them, and Their Uses | NR1H3, NR1I3, NR1I2 | NPC1 638/4885HPGD 1830/4885TP53 4539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.