Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | PLAU | P00749 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090404 | 0.85 | TP53 (0.42) | MRGPRX4TP53HPGDSMN1; SMN2HRH3 | |
| SCHEMBL2087120 | 0.83 | TP53 (0.40) | MRGPRX4TP53HPGDSMN1; SMN2HRH3 | |
| SCHEMBL2088703 | 0.74 | NPC1 (0.38) | TP53HPGDSMN1; SMN2HRH3LMNA | |
| SCHEMBL12379039 | 0.72 | KMT2A (0.41) | TP53HPGDSMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL25435826 | 0.72 | KMT2A (0.38) | TP53HPGDSMN1; SMN2DHODHALDH1A1 | |
| SCHEMBL2938443 | 0.70 | HPGD (0.41) | TP53HPGDSMN1; SMN2HRH3ALDH1A1 | |
| SCHEMBL27747426 | 0.70 | KMT2A (0.44) | TP53HPGDSMN1; SMN2DHODHALDH1A1 | |
| SCHEMBL28542992 | 0.69 | ALDH1A1 (0.43) | TP53HPGDSMN1; SMN2LMNADHODH | |
| SCHEMBL11168021 | 0.69 | ALDH1A1 (0.50) | HPGDSMN1; SMN2HRH3ALDH1A1MAPT | |
| SCHEMBL29912337 | 0.69 | PLA2G2A (0.49) | TP53THRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863450-B2 | Compounds comprising an oxazoline or thiazoline moiety, processes for making them, and their uses | UCB PHARMA, S.A. (BE) | 2011-01-04 | — | — | US | disclosed |