SCHEMBL20878548

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17992977	1.00	TAAR1 (0.59)	TAAR1SIGMAR1SLC18A2SLC6A2MAOA
	Dextroamphetamine SCHEMBL1435827	0.77	TAAR1 (0.86)	TAAR1SIGMAR1SLC18A2SLC6A2MAOA
	SCHEMBL4091905	0.77	TAAR1 (0.59)	TAAR1SIGMAR1SLC18A2SLC6A2MAOA
	Methamphetamine SCHEMBL9824299	0.77	SIGMAR1 (0.84)	TAAR1SIGMAR1SLC18A2SLC6A2MAOA
	SCHEMBL1697045	0.76	SIGMAR1 (0.64)	TAAR1SIGMAR1SLC18A2SLC6A2MAOA
	SCHEMBL11783693	0.76	EPHX1 (0.54)	TAAR1SIGMAR1SLC6A2MAOASLC6A4
	SCHEMBL18032935	0.76	SIGMAR1 (0.59)	TAAR1SIGMAR1SLC6A2MAOASLC6A4
	Methamphetamine SCHEMBL13737281	0.75	TAAR1 (0.81)	TAAR1SIGMAR1SLC18A2SLC6A2MAOA
	Methamphetamine SCHEMBL4083435	0.75	TAAR1 (0.81)	TAAR1SIGMAR1SLC18A2SLC6A2MAOA
	SCHEMBL20403618	0.75	TAAR1 (0.52)	TAAR1SIGMAR1SLC18A2SLC6A2MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.