Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20055714 | 1.00 | LMNA (0.46) | LMNATAAR1TRPA1AOC3KMT2A | |
| SCHEMBL27994440 | 0.83 | AOC3 (0.42) | LMNATAAR1TRPA1AOC3KMT2A | |
| SCHEMBL1293117 | 0.76 | LMNA (0.50) | LMNATAAR1TRPA1AOC3KMT2A | |
| SCHEMBL3627329 | 0.76 | LMNA (0.50) | LMNATAAR1TRPA1AOC3KMT2A | |
| SCHEMBL807041 | 0.75 | TAAR1 (0.44) | LMNATAAR1AOC3MIFCYP2D6 | |
| SCHEMBL9023354 | 0.75 | TAAR1 (0.42) | LMNATAAR1MIFCYP2D6 | |
| SCHEMBL22009966 | 0.74 | HKDC1 (0.52) | LMNATAAR1TRPA1AOC3KMT2A | |
| SCHEMBL11721312 | 0.74 | DPP4 (0.47) | LMNATAAR1HTR2AHRH1CYP2D6 | |
| SCHEMBL22062330 | 0.74 | TAAR1 (0.41) | LMNATAAR1TRPA1AOC3KMT2A | |
| SCHEMBL21120565 | 0.73 | TAAR1 (0.41) | LMNATAAR1MIFCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2953957-B1 | MODIFIED GLYCOLIPIDS AND METHODS OF MAKING AND USING THE SAME | VACCINEX INC (US) | 2019-04-10 | — | — | EP | disclosed |