SCHEMBL208822

SCHEMBL208822

Cc1ccc([SiH2]c2ccc(C)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 6/20 0.61
TDP1 Q9NUW8 1/20 0.61
CA2 P00918 2/20 0.45
LPL P06858 1/20 0.45
LIPG Q9Y5X9 1/20 0.45
ORAI1 Q96D31 1/20 0.45
ORAI2 Q96SN7 1/20 0.45
ORAI3 Q9BRQ5 1/20 0.45
TRPV6 Q9H1D0 1/20 0.45
ALDH1A1 P00352 4/20 0.44
CA1 P00915 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
TSHR P16473 3/20 0.41
LMNA P02545 2/20 0.41
ALOX12 P18054 1/20 0.41
CYP2A6 P11509 3/20 0.38
IDO1 P14902 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16301269 1.00 ACHE (0.61) ACHETDP1CA2LPLLIPG
Hydrochloric Acid SCHEMBL28008993 0.96 ACHE (0.57) ACHETDP1CA2LPLLIPG
SCHEMBL9318204 0.87 ACHE (0.56) ACHETDP1CA2LPLLIPG
SCHEMBL277305 0.81 ACHE (0.57) ACHETDP1CA2LPLLIPG
SCHEMBL24849340 0.81 ACHE (0.75) ACHETDP1CA2ALDH1A1CA1
SCHEMBL1054364 0.79
P-Xylene SCHEMBL460348 0.78 ACHE (1.00) ACHETDP1CA2LPLLIPG
P-Xylene SCHEMBL771 0.78
P-Xylene SCHEMBL11772917 0.78 ACHE (1.00) ACHETDP1CA2LPLLIPG
P-Xylene SCHEMBL11770184 0.78 ACHE (1.00) ACHETDP1CA2LPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 752 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240002400-A1 ENANTIOSELECTIVE ALKENYLATION OF ALDEHYDES AMGEN INC. (US) 2024-01-04 US claimed
EP-4251604-A1 ENANTIOSELECTIVE ALKENYLATION OF ALDEHYDES Amgen Inc. (US) 2023-10-04 EP claimed
CN-116745258-A Enantioselective alkenylation of aldehydes 安进公司 2023-09-12 CN claimed
CN-115557983-A Organic silanol compound containing S-S bond and preparation method thereof 苏州照固新材料科技有限公司 2023-01-03 CN claimed
WO-2022115400-A1 ENANTIOSELECTIVE ALKENYLATION OF ALDEHYDES AMGEN INC. (US) 2022-06-02 WO claimed
CN-107722277-A A kind of preparation method of hybrid particle 西北工业大学 2018-02-23 CN claimed
US-6639030-B2 Using coordination catalyst TOSOH CORPORATION (JP) 2003-10-28 US claimed
US-3939137-A OLEFIN POLYMERIZATION PHILLIPS PETROLEUM COMPANY (US) 1976-02-17 US claimed
US-12043679-B2 On-line adjustment of mixed catalyst ratio by trim and olefin polymerization with the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2024-07-23 US disclosed
EP-3283536-B1 CATALYSTS FOR CONTROL OF LONG CHAIN BRANCHING UNIVATION TECH LLC (US) 2024-07-17 EP disclosed
CN-111240157-B Positive photosensitive resin composition and cured film prepared therefrom 罗门哈斯电子材料韩国有限公司 2024-07-09 CN disclosed
WO-2024129637-A1 DECREASING TRIBOELECTRIC CHARGING OF, AND/OR REACTOR FOULING BY, POLYOLEFIN PARTICLES UNIVATION TECHNOLOGIES, LLC (US) 2024-06-20 WO disclosed
WO-2024116861-A1 CURABLE RESIN, CURABLE RESIN COMPOSITION, AND CURED ARTICLE DIC株式会社 2024-06-06 WO disclosed
US-11976140-B2 In-line trimming of dry catalyst feed EXXONMOBIL CHEMICAL PATENTS INC. (US) 2024-05-07 US disclosed
WO-1994007927-A1 CATALYST SYSTEM OF ENHANCED PRODUCTIVITY AND ITS USE IN POLYMERIZATION PROCESS EXXON CHEMICAL PATENTS INC. (US) 1994-04-14 WO disclosed
EP-0551771-A2 Process for producing polysilanes NIPPON OIL CO. LTD. (JP) 1993-07-21 EP disclosed
EP-0514034-A1 Silane products from reaction of solid silicon monoxide with aromatic halides DOW CORNING CORPORATION (US) 1992-11-19 EP disclosed
US-5120520-A In presence of metal or metal-contianing catalyst DOW CORNING CORPORATION (US) 1992-06-09 US disclosed
US-4014816-A OLEFIN POLYMERIZATION PHILLIPS PETROLEUM COMPANY (US) 1977-03-29 US disclosed
US-3939137-A OLEFIN POLYMERIZATION PHILLIPS PETROLEUM COMPANY (US) 1976-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240002400-A1 ENANTIOSELECTIVE ALKENYLATION OF ALDEHYDES MCL1, BAK1, BCL2A1 ACHE 4503/4885TDP1 867/4885CA2 4405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.