Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 12/20 | 0.62 |
| ▸ | CNR1 | P21554 | 4/20 | 0.55 |
| ▸ | CNR2 | P34972 | 4/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 5/20 | 0.52 |
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15247218 | 0.98 | FAAH (0.59) | FAAHCNR1CNR2HSP90AA1CES1 | |
| SCHEMBL14842883 | 0.92 | FAAH (0.50) | FAAHCNR1CNR2HSP90AA1CES1 | |
| Trifluoroacetic Acid SCHEMBL28247260 | 0.91 | FAAH (0.52) | FAAHCNR1CNR2CES1CES2 | |
| SCHEMBL4565411 | 0.84 | CASP2 (0.47) | FAAHCNR1CNR2 | |
| SCHEMBL13701833 | 0.82 | FAAH (0.64) | FAAHHSP90AA1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5707324 | 0.82 | CASP2 (0.45) | FAAHCNR1CNR2KMT2A | |
| SCHEMBL15474110 | 0.81 | FAAH (0.61) | FAAHCNR1CNR2HSP90AA1 | |
| SCHEMBL31560149 | 0.81 | FAAH (0.62) | FAAHCNR1CNR2HSP90AA1MEN1 | |
| SCHEMBL13621278 | 0.81 | FAAH (0.62) | FAAHCNR1CNR2HSP90AA1MEN1 | |
| SCHEMBL12572413 | 0.81 | FAAH (0.62) | FAAHCNR1CNR2HSP90AA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200290950-A1 | ALKAMIDE COMPOUNDS AND USES THEREOF | NORTH CAROLINA STATE UNIVERSITY | 2020-09-17 | — | — | US | disclosed |
| WO-2019071093-A1 | ALKAMIDE COMPOUNDS AND USES THEREOF | NORTH CAROLINA STATE UNIVERSITY (US) | 2019-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200290950-A1 | ALKAMIDE COMPOUNDS AND USES THEREOF | ALK, ENPP2, CYSLTR2 | FAAH 25/4885CNR1 85/4885CNR2 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.