Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA3 | P32297 | 5/20 | 0.81 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.76 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2089449 | 0.90 | CHRNA3 (1.00) | CHRNA3KCNH2CHRNA7 | |
| SCHEMBL2055637 | 0.85 | CHRNA3 (0.84) | CHRNA3KCNH2CHRNA7 | |
| SCHEMBL1854943 | 0.85 | KCNH2 (1.00) | CHRNA3KCNH2CHRNA7 | |
| Hydrochloric Acid SCHEMBL1863445 | 0.84 | KCNH2 (0.98) | CHRNA3KCNH2CHRNA7 | |
| SCHEMBL2089789 | 0.84 | KCNH2 (0.98) | CHRNA3KCNH2CHRNA7 | |
| Hydrochloric Acid SCHEMBL4085058 | 0.83 | KCNH2 (0.97) | CHRNA3KCNH2CHRNA7 | |
| SCHEMBL13660049 | 0.81 | CHRNA3 (0.71) | CHRNA3KCNH2CHRNA7 | |
| SCHEMBL4173930 | 0.80 | CHRNA3 (0.70) | CHRNA3KCNH2CHRNA7 | |
| SCHEMBL1856137 | 0.80 | CHRNA3 (0.70) | CHRNA3KCNH2CHRNA7 | |
| SCHEMBL13660066 | 0.78 | KCNH2 (0.84) | CHRNA3KCNH2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163729-B2 | Modulators of α7 nicotinic acetylcholine receptors and therapeutic uses thereof | WYETH (US) | 2012-04-24 | — | — | US | disclosed |