Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA3 | P32297 | 3/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.68 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.63 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.57 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13660049 | 0.90 | CHRNA3 (0.71) | CHRNA3KCNH2CHRNA7CSNK2A2CSNK2A1 | |
| SCHEMBL1856137 | 0.89 | CHRNA3 (0.70) | CHRNA3KCNH2CHRNA7CSNK2A2CSNK2A1 | |
| SCHEMBL7930564 | 0.83 | CSNK2A2 (0.65) | CHRNA3KCNH2CSNK2A2CSNK2A1NPY5R | |
| SCHEMBL2089449 | 0.82 | CHRNA3 (1.00) | CHRNA3KCNH2CHRNA7 | |
| SCHEMBL2088367 | 0.80 | CHRNA3 (0.81) | CHRNA3KCNH2CHRNA7 | |
| SCHEMBL2055637 | 0.79 | CHRNA3 (0.84) | CHRNA3KCNH2CHRNA7 | |
| SCHEMBL6395915 | 0.78 | CSNK2A2 (0.58) | CHRNA3KCNH2CSNK2A2CSNK2A1NPY5R | |
| SCHEMBL1854943 | 0.78 | KCNH2 (1.00) | CHRNA3KCNH2CHRNA7 | |
| SCHEMBL6583002 | 0.78 | NPY5R (0.65) | CHRNA3KCNH2CSNK2A2CSNK2A1NPY5R | |
| Hydrochloric Acid SCHEMBL1863445 | 0.77 | KCNH2 (0.98) | CHRNA3KCNH2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264648-A1 | SYNTHESIS OF PYRAZOLES | WYETH (US) | 2009-10-22 | — | — | US | disclosed |
| WO-2009091832-A1 | SYNTHESIS OF PYRAZOLES | WYETH (US) | 2009-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264648-A1 | SYNTHESIS OF PYRAZOLES | CHRNA7, CHRNA5, CHRNA3 | CHRNA3 3/4885KCNH2 616/4885CHRNA7 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.