SCHEMBL2088409

SCHEMBL2088409

Clc1ncc(CI)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2091057 0.80
SCHEMBL486327 0.80
SCHEMBL335264 0.77
SCHEMBL2090380 0.75
SCHEMBL281998 0.75
SCHEMBL464607 0.75
SCHEMBL155863 0.75
SCHEMBL13221313 0.75
SCHEMBL1274373 0.75
Hydrochloric Acid SCHEMBL3117520 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104755476-B Method for producing compound 住友化学株式会社 2017-12-05 CN disclosed
WO-2017141049-A1 METHYLAMINE DERIVATIVES AS LYSYSL OXIDASE INHIBITORS FOR THE TREATMENT OF CANCER THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2017-08-24 WO disclosed
WO-2017048950-A1 HEPATITIS B CORE PROTEIN MODULATORS ASSEMBLY BIOSCIENCES, INC. (US) 2017-03-23 WO disclosed
EP-1732895-B1 INSECTICIDAL N-SUBSTITUTED SULFOXIMINES DOW AGROSCIENCES LLC (US) 2016-11-16 EP disclosed
WO-2015091649-A1 N-SUBSTITUTED IMINO HETEROCYCLIC COMPOUNDS BASF SE (DE) 2015-06-25 WO disclosed
EP-1756075-B1 COMPOUND FOR PREPARING THIAZOLE BY AMINOMETHYLATION SUMITOMO CHEMICAL CO (JP) 2013-08-07 EP disclosed
CN-1942442-B Insecticidal N-substituted sulfenimides DOW AGROSCIENCES LLC 2012-10-31 CN disclosed
CN-101648906-B Insecticidal N-substituted sulfoximines DOW AGROSCIENCES LLC 2012-07-11 CN disclosed
EP-1866297-B1 PROCESS FOR PRODUCING AN AMINOMETHYL THIAZOLE COMPOUND SUMITOMO CHEMICAL CO (JP) 2011-12-28 EP disclosed
US-7977490-B2 Process for producing thiazole compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-12 US disclosed
CN-1942442-A Insecticidal N-substituted sulfenimides DOW AGROSCIENCES LLC (US) 2007-04-04 CN disclosed
EP-1756075-A1 COMPOUND FOR PREPARING THIAZOLE BY AMINOMETHYLATION Sumitomo Chemical Company, Limited (JP) 2007-02-28 EP disclosed
EP-1732895-A2 INSECTICIDAL N-SUBSTITUTED SULFOXIMINES Dow Agrosciences LLC (US) 2006-12-20 EP disclosed
WO-2006109811-A1 PROCESS FOR PRODUCING AN AMINOMETHYL THIAZOLE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-10-19 WO disclosed
WO-2006060029-A2 INSECTICIDAL N-SUBSTITUTED SULFOXIMINES DOW AGROSCIENCES LLC (US) 2006-06-08 WO disclosed
WO-2005123704-A1 COMPOUND FOR PREPARING THIAZOLE BY AMINOMETHYLATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-12-29 WO disclosed
US-20050228027-A1 Insecticidal N-substituted sulfoximines CORTEVA AGRISCIENCE LLC 2005-10-13 US disclosed
US-6265585-B1 REACTING 2-CHLORO-5-HYDROXYMETHYLTHIAZOLE WITH SULFONYLATING AGENT SYNGENTA CROP PROTECTION, INC. 2001-07-24 US disclosed
EP-0958286-A1 PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES Novartis AG (CH) 1999-11-24 EP disclosed
WO-1998032747-A1 PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES NOVARTIS AG (CH) 1998-07-30 WO disclosed