SCHEMBL281998

SCHEMBL281998

OCc1cnc(Cl)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7107224 0.98
SCHEMBL12289411 0.78
SCHEMBL335264 0.77
SCHEMBL6234352 0.75
SCHEMBL606580 0.75
Hydrochloric Acid SCHEMBL3117520 0.75
SCHEMBL2956791 0.75
SCHEMBL155863 0.75
SCHEMBL13221313 0.75
SCHEMBL2088409 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111303069-A Clothianidin residual liquid recovery method 岳阳市宇恒化工有限公司 2020-06-19 CN claimed
CN-104419326-A Slurry composition for chemical mechanical polishing COWON INNOTECH INC 2015-03-18 CN claimed
US-8841296-B2 Substituted 1, 4-dioxa-8-azaspiro[4,5]decanes useful as fungicides and a process for the preparation thereof Council of Scientific and Industrial Research, Anusandhan Bhawan, Rafi Marg (IN) 2014-09-23 US claimed
CN-101863853-B Technique for preparing 5-hydroxymethyl thiazole by one pot method ANHUI BIOCHEM UNITED PHARMACEUTICAL CO LTD 2012-12-19 CN claimed
US-20120225877-A1 SUBSTITUTED 1, 4-DIOXA-8-AZASPIRO[4,5]DECANES USEFUL AS FUNGICIDES AND A PROCESS FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH; ANUSANDHAN BHAWAN, RAFI MARG. (IN) 2012-09-06 US claimed
CN-101914073-B Preparation method of 5-hydroxymethylthiazole TIANJIN WEIJIE TECHNOLOGY CO LTD 2012-07-11 CN claimed
CN-101613325-B Process for producing 5-hydroxymethylthiazole CUICENG YE 2011-09-14 CN claimed
CN-101914073-A Preparation method of 5-hydroxymethylthiazole TIANJIN WEIJIE TECHNOLOGY CO LTD 2010-12-15 CN claimed
CN-101863853-A Technique for preparing 5-hydroxymethyl thiazole by one pot method ANHUI BIOCHEM UNITED PHARMACEUTICAL CO LTD 2010-10-20 CN claimed
WO-2010109299-A2 SUBSTITUTED 1, 4-DIOXA-8-AZASPIRO [4,5] DECANES USEFUL AS FUNGICIDES AND A PROCESS FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2010-09-30 WO claimed
CN-1368966-A Process for preparing thiazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2002-09-11 CN claimed
EP-1202979-A1 PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES Syngenta Participations AG (CH) 2002-05-08 EP claimed
EP-0793659-B1 PROCESS FOR PREPARATION OF 5-HYDROXYMETHYLTHIAZOLE ABBOTT LAB (US) 2001-03-14 EP claimed
WO-2001010852-A1 PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2001-02-15 WO claimed
EP-1007517-A1 PROCESS FOR THE PREPARATION OF 5-HYDROXYMETHYLTHIAZOLES Abbott Laboratories (US) 2000-06-14 EP claimed
WO-1999011636-A1 PROCESS FOR THE PREPARATION OF 5-HYDROXYMETHYLTHIAZOLES ABBOTT LABORATORIES (US) 1999-03-11 WO claimed
WO-1998045279-A1 PREPARATION OF THIAZOLES USING 1,3-DIHALOPROPENES REILLY INDUSTRIES, INC. (US) 1998-10-15 WO claimed
US-5712400-A Process for preparation of 5-hydroxymethylthiazole ABBOTT LABORATORIES (US) 1998-01-27 US claimed
EP-0793659-A1 PROCESS FOR PREPARATION OF 5-HYDROXYMETHYLTHIAZOLE Abbott Laboratories (US) 1997-09-10 EP claimed
WO-1996016050-A1 PROCESS FOR PREPARATION OF 5-HYDROXYMETHYLTHIAZOLE ABBOTT LABORATORIES (US) 1996-05-30 WO claimed