Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.47 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.47 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.47 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.47 |
| ▸ | STIM2 | Q9P246 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20807633 | 0.91 | KDM4E (0.46) | KDM4EHPGDALDH1A1MAPTL3MBTL1 | |
| SCHEMBL23039063 | 0.91 | KDM4E (0.46) | KDM4EHPGDALDH1A1MAPTL3MBTL1 | |
| SCHEMBL23065853 | 0.91 | KDM4E (0.46) | KDM4EHPGDALDH1A1MAPTL3MBTL1 | |
| SCHEMBL2088074 | 0.86 | KDM4E (0.50) | KDM4EHPGDALDH1A1MAPTL3MBTL1 | |
| SCHEMBL23065877 | 0.85 | KDM4E (0.42) | KDM4EHPGDALDH1A1MAPTL3MBTL1 | |
| SCHEMBL23065622 | 0.85 | KDM4E (0.42) | KDM4EHPGDALDH1A1MAPTL3MBTL1 | |
| SCHEMBL28436894 | 0.85 | KDM4E (0.42) | KDM4EHPGDALDH1A1MAPTL3MBTL1 | |
| SCHEMBL2089336 | 0.84 | KDM4E (0.48) | KDM4EHPGDALDH1A1MAPTL3MBTL1 | |
| SCHEMBL31668513 | 0.84 | KDM4E (0.44) | KDM4EHPGDALDH1A1MAPTL3MBTL1 | |
| SCHEMBL13126505 | 0.83 | ALDH1A1 (0.50) | KDM4EHPGDALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1854788-B1 | METHOD FOR PRODUCING 1-SUBSTITUTED-3-FLUOROALKYL PYRAZOLE-4-CARBOXYLATE | SAGAMI CHEM RES (JP) | 2012-06-13 | — | — | EP | disclosed |
| US-7863460-B2 | Process for producing 1-substituted-3-fluoroalkylpyrazole-4-carboxylate | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2011-01-04 | — | — | US | disclosed |
| US-7863460-B2 | Process for producing 1-substituted-3-fluoroalkylpyrazole-4-carboxylate | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2011-01-04 | — | — | US | disclosed |
| US-20080154045-A1 | Process for Producing 1-Substituted-3-Fluoroalkylpyrazole-4-Carboxylate | SAGAMI CHEMICAL RESEARCKH CENTER (JP) | 2008-06-26 | — | — | US | disclosed |
| US-20080154045-A1 | Process for Producing 1-Substituted-3-Fluoroalkylpyrazole-4-Carboxylate | SAGAMI CHEMICAL RESEARCKH CENTER (JP) | 2008-06-26 | — | — | US | disclosed |
| EP-1854788-A1 | METHOD FOR PRODUCING 1-SUBSTITUTED-3-FLUOROALKYL PYRAZOLE-4-CARBOXYLATE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2007-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080154045-A1 | Process for Producing 1-Substituted-3-Fluoroalkylpyrazole-4-Carboxylate | CYP4Z1, CYP3A4, HACL2 | KDM4E 1021/4885HPGD 1081/4885ALDH1A1 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.