Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20887227 | 0.91 | LMNA (0.57) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20887230 | 0.89 | LMNA (0.55) | MEN1KMT2AKCNH2 | |
| SCHEMBL2156435 | 0.85 | ALDH1A1 (0.67) | MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL20887060 | 0.83 | TSHR (0.50) | KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL20887056 | 0.83 | HSD17B10 (0.55) | KMT2AMAPT | |
| SCHEMBL20887048 | 0.83 | TSHR (0.50) | KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11100857 | 0.82 | ALDH1A1 (0.75) | MAPTSMN1; SMN2KCNH2 | |
| SCHEMBL6714846 | 0.82 | ALDH1A1 (0.75) | MAPTSMN1; SMN2KCNH2 | |
| SCHEMBL20887239 | 0.81 | MEN1 (0.56) | MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL20887231 | 0.81 | MEN1 (0.70) | MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019071104-A1 | COMPOSITIONS AND METHODS FOR PREVENTION AND TREATMENT OF HYPERAMMONEMIA | CHILDREN'S NATIONAL MEDICAL CENTER (US) | 2019-04-11 | — | — | WO | disclosed |