Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 1/20 | 0.75 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.75 |
| ▸ | HTR1A | P08908 | 2/20 | 0.74 |
| ▸ | HTR2A | P28223 | 2/20 | 0.74 |
| ▸ | HTR7 | P34969 | 2/20 | 0.74 |
| ▸ | HTR6 | P50406 | 2/20 | 0.74 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.74 |
| ▸ | HTR3B | O95264 | 2/20 | 0.74 |
| ▸ | HTR3A | P46098 | 2/20 | 0.74 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.74 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.74 |
| ▸ | THRB | P10828 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100857 | 1.00 | ALDH1A1 (0.75) | ALDH1A1LMNAMAPTALOX12SMN1; SMN2 | |
| SCHEMBL9646111 | 0.94 | ALDH1A1 (0.73) | ALDH1A1LMNAMAPTALOX12SMN1; SMN2 | |
| SCHEMBL29595602 | 0.91 | HTR3E (0.69) | ALDH1A1LMNAMAPTALOX12SMN1; SMN2 | |
| SCHEMBL26770369 | 0.91 | HTR3E (0.69) | ALDH1A1LMNAMAPTALOX12SMN1; SMN2 | |
| SCHEMBL1822683 | 0.91 | HTR3E (0.69) | ALDH1A1LMNAMAPTALOX12SMN1; SMN2 | |
| SCHEMBL30407444 | 0.91 | HTR3E (0.69) | ALDH1A1LMNAMAPTALOX12SMN1; SMN2 | |
| SCHEMBL11210900 | 0.90 | ALDH1A1 (0.69) | ALDH1A1LMNAMAPTALOX12SMN1; SMN2 | |
| SCHEMBL1384496 | 0.90 | HTR1A (0.65) | ALDH1A1LMNAMAPTALOX12SMN1; SMN2 | |
| SCHEMBL1384498 | 0.90 | KCNH2 (0.65) | ALDH1A1LMNAMAPTALOX12SMN1; SMN2 | |
| SCHEMBL11922752 | 0.89 | HTR3E (0.67) | ALDH1A1LMNAMAPTALOX12SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040123555-A1 | Pre manufactured structural panel consisting of a flame retardant external crust and an aeroboard core fabricated from laminations of uncompressed cardboard, impregnated by resin solutions recovered from post consumer thermoplastics | COLE JEFFERSON ANTHONY (TT) | 2004-07-01 | — | — | US | claimed |
| EP-0251011-B1 | INDOLYL PROPIONIC ACIDS | BAYER AG (DE) | 1990-10-24 | — | — | EP | disclosed |
| US-4843091-A | Indolylpropionic acids, compositions of, and use thereof to inhibit thrombocyte aggregation | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-27 | — | — | US | disclosed |
| EP-0251011-A1 | Indolyl propionic acids | BAYER AG (DE) | 1988-01-07 | — | — | EP | disclosed |
| US-4477635-A | Polymeric triarylmethane dyes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-10-16 | — | — | US | disclosed |