Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20895231 | 0.83 | RIPK1 (0.42) | SLC9A1RIPK1ALDH1A1 | |
| SCHEMBL443241 | 0.83 | SMN1; SMN2 (0.33) | SLC9A1KDM4EALDH1A1 | |
| SCHEMBL28288044 | 0.80 | ALDH1A1 (0.38) | KDM4EALDH1A1 | |
| SCHEMBL21295797 | 0.78 | F9 (0.41) | SLC9A1ALDH1A1 | |
| SCHEMBL18889257 | 0.77 | SLC9A1 (0.41) | SLC9A1RIPK1 | |
| SCHEMBL20895159 | 0.75 | F9 (0.40) | SLC9A1ALDH1A1 | |
| SCHEMBL20895112 | 0.75 | SLC9A1 (0.44) | SLC9A1RIPK1KDM4E | |
| SCHEMBL21295608 | 0.71 | KDM4E (0.41) | KDM4EALDH1A1 | |
| SCHEMBL20895115 | 0.70 | ABL1 (0.39) | KDM4EALDH1A1 | |
| SCHEMBL21295808 | 0.70 | PIK3CD (0.44) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3176163-B1 | NOVEL INDENE DERIVATIVE, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING RETINAL DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | IAC IN NAT UNIV CHUNGNAM (KR) | 2019-04-17 | — | — | EP | claimed |
| EP-3176163-B1 | NOVEL INDENE DERIVATIVE, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING RETINAL DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | IAC IN NAT UNIV CHUNGNAM (KR) | 2019-04-17 | — | — | EP | disclosed |