SCHEMBL2089563

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2094481	0.89	CHRM3 (0.42)	CES2CYP1A2CYP2C19CYP2D6RAB9A
	SCHEMBL2096162	0.82	MAPT (0.51)	CES2CYP1A2CYP2C19CYP2D6RAB9A
	SCHEMBL5542350	0.81	ALDH1A1 (0.49)	CES2CYP1A2CYP2C19CYP2D6RAB9A
	SCHEMBL4439565	0.78	RXFP1 (0.54)	CES2CYP1A2CYP2C19CYP2D6RAB9A
	SCHEMBL5538010	0.78	ALDH1A1 (0.47)	CES2CYP1A2CYP2C19CYP2D6RAB9A
	SCHEMBL2088749	0.77	EPHX2 (0.58)	RAB9AMEN1KMT2AMGLLTRPV1
	SCHEMBL2099764	0.75	HPGD (0.41)	CYP1A2CYP2C19CYP2D6MEN1KMT2A
	SCHEMBL2094340	0.75	MAPT (0.61)	RAB9AMEN1KMT2AALDH1A1MGLL
	SCHEMBL5544752	0.75	CYP1A2 (0.56)	CES2CYP1A2CYP2C19CYP2D6RAB9A
	SCHEMBL4796235	0.75	KIF11 (0.59)	CES2CYP1A2CYP2C19CYP2D6RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.