SCHEMBL2089640

SCHEMBL2089640

CCCC1(c2ccccc2)CCCCC1

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 4/20 0.59
SLC6A2 P23975 3/20 0.59
SLC6A3 Q01959 3/20 0.59
DPP4 P27487 1/20 0.57
S1PR1 P21453 1/20 0.48
S1PR3 Q99500 1/20 0.48
CHRM2 P08172 1/20 0.45
CHRM1 P11229 1/20 0.45
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
TAAR1 Q96RJ0 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10607505 0.94 DPP4 (0.53) SLC6A4SLC6A2SLC6A3DPP4S1PR1
SCHEMBL6021772 0.90 MAOA (0.56) SLC6A4SLC6A2SLC6A3DPP4MAOA
SCHEMBL15568275 0.89 SLC6A4 (0.56) SLC6A4SLC6A2SLC6A3DPP4S1PR1
SCHEMBL28280766 0.87 SLC6A4 (0.59) SLC6A4SLC6A2SLC6A3DPP4S1PR1
SCHEMBL10590819 0.85 SLC6A4 (0.57) SLC6A4SLC6A2SLC6A3DPP4S1PR1
SCHEMBL4822872 0.84 SLC6A3 (0.53) SLC6A4SLC6A2SLC6A3
SCHEMBL5853830 0.83 SLC6A4 (0.63) SLC6A4SLC6A2SLC6A3DPP4CHRM2
SCHEMBL29201208 0.83 SLC6A4 (0.42) SLC6A4SLC6A2SLC6A3DPP4MAOA
SCHEMBL21369229 0.82 CNR1 (0.46) SLC6A4SLC6A2SLC6A3
SCHEMBL10608925 0.82 OPRM1 (0.50) SLC6A4SLC6A2SLC6A3DPP4S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110041275-B 4-propylcyclohexylbenzene derivative containing 1,2, 3-triazole five-membered ring and preparation method thereof 四川师范大学 2022-07-01 CN claimed
WO-2023245790-A1 METHOD FOR PREPARING CYCLOALKANE FROM CYCLIC ALCOHOL IN ONE STEP BY MEANS OF MOLECULAR SIEVE 中节能万润股份有限公司 2023-12-28 WO disclosed
CN-114890857-B Method for preparing cycloalkane from cyclic alcohol in one step through molecular sieve 中节能万润股份有限公司 2023-04-07 CN disclosed
CN-114890857-A Method for preparing cycloalkane from cyclic alcohol in one step through molecular sieve 中节能万润股份有限公司 2022-08-12 CN disclosed
CN-107828426-A Liquid crystal medium and liquid crystal display device 达兴材料股份有限公司 2018-03-23 CN disclosed
EP-1731587-B1 Process for the preparation of tolanes MERCK PATENT GMBH (DE) 2013-01-23 EP disclosed
EP-1867372-B1 METHOD FOR CRYSTALLIZATION OF PARAXYLENE THROUGH ADIABATIC COOLING TSUKISHIMA KIKAI CO (JP) 2012-10-10 EP disclosed
EP-1867373-B1 METHOD FOR CRYSTALLIZATION OF PARAXYLENE THROUGH ADIABATIC COOLING TSUKISHIMA KIKAI CO (JP) 2012-08-22 EP disclosed
US-8163970-B2 Method for adiabatic cooling type crystallization of organic compound and apparatus therefor TSUKISHIMA KIKAI CO., LTD. (JP) 2012-04-24 US disclosed
CN-1896040-B Tolanes, process for their preparation and use thereof MERCK PATENT GMBH 2011-08-10 CN disclosed
EP-1329259-A2 Continuous method for hydrolysis of a solvent containing organic compound MERCK PATENT GmbH (DE) 2003-07-23 EP disclosed
WO-1999015524-A1 THIAZOLE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-04-01 WO disclosed
EP-0139643-B1 LIQUID CRYSTAL TUNED BIREFRINGENT FILTER BECKMAN INSTRUMENTS, INC. (US) 1989-11-29 EP disclosed
US-4600300-A Method and apparatus to determine frequency of movement and for visual inspection of moving objects ROTELLO GREGORY A 1986-07-15 US disclosed
EP-0139643-A1 LIQUID CRYSTAL TUNED BIREFRINGENT FILTER. BECKMAN INSTRUMENTS INC (US) 1985-05-08 EP disclosed
US-4497542-A Apparatus for minimizing beam collimation sensitivity in optical instruments including liquid crystal cells BECKMAN INSTRUMENTS, INC. (US) 1985-02-05 US disclosed
WO-1984004402-A1 LIQUID CRYSTAL TUNED BIREFRINGENT FILTER BECKMAN INSTRUMENTS INC (US) 1984-11-08 WO disclosed
US-4444469-A Narrow band rejection filter utilizing a liquid crystal cell BECKMAN INSTRUMENTS, INC. (US) 1984-04-24 US disclosed
US-4394069-A Liquid crystal tuned birefringent filter BECKMAN INSTRUMENTS, INC. (US) 1983-07-19 US disclosed
US-4272195-A Method and apparatus for determining the wavelength of light BECKMAN INSTRUMENTS, INC. (US) 1981-06-09 US disclosed