Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.38 |
| ▸ | TUBB | P07437 | 2/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29602867 | 1.00 | ASAH1 (0.43) | ASAH1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29369659 | 0.88 | TUBB4A (0.41) | ASAH1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20591983 | 0.88 | TUBB4A (0.41) | ASAH1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29354525 | 0.82 | TUBB4A (0.44) | ASAH1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1277493 | 0.82 | TUBB4A (0.44) | ASAH1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29803806 | 0.80 | TUBB4A (0.41) | ASAH1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6372854 | 0.78 | TUBB4A (0.41) | ASAH1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6896839 | 0.76 | ASAH1 (0.47) | ASAH1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL21176002 | 0.75 | TUBB4A (0.40) | ASAH1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL25431414 | 0.74 | ASAH1 (0.47) | ASAH1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077306-B1 | COMPOUNDS AND PROBES FOR IMAGING HUNTINGTIN PROTEIN | CHDI FOUNDATION INC (US) | 2025-05-07 | — | — | EP | disclosed |
| US-11918662-B2 | Heterocyclic compounds and imaging agents for imaging huntingtin protein | CHDI FOUNDATION, INC. (US) | 2024-03-05 | — | — | US | disclosed |
| US-20210393812-A1 | HETEROCYCLIC COMPOUNDS AND IMAGING AGENTS FOR IMAGING HUNTINGTIN PROTEIN | CHDI FOUNDATION, INC. | 2021-12-23 | — | — | US | disclosed |
| US-10793578-B2 | Fused pentacyclic imidazole derivatives as modulators of TNF activity | UCB Biopharma SRL (BE) | 2020-10-06 | — | — | US | disclosed |
| US-20190112314-A1 | Fused Pentacyclic Imidazole Derivatives as Modulators of TNF Activity | UCB BIOPHARMA SPRL (BE) | 2019-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11918662-B2 | Heterocyclic compounds and imaging agents for imaging huntingtin protein | HTT, HYPK, HSPBP1 | ASAH1 4028/4885TUBB4A 1236/4885TUBB 1379/4885 |
| US-20190112314-A1 | Fused Pentacyclic Imidazole Derivatives as Modulators of TNF Activity | TNF, TNFRSF1A, NFKBIA | ASAH1 2399/4885TUBB4A 824/4885TUBB 340/4885 |
| US-20210393812-A1 | HETEROCYCLIC COMPOUNDS AND IMAGING AGENTS FOR IMAGING HUNTINGTIN PROTEIN | HTT, HYPK, HSPBP1 | ASAH1 4028/4885TUBB4A 1236/4885TUBB 1379/4885 |
| US-10793578-B2 | Fused pentacyclic imidazole derivatives as modulators of TNF activity | TNF, TNFRSF1A, NFKBIA | ASAH1 2399/4885TUBB4A 824/4885TUBB 340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.