Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.66 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.60 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | GUSB | P08236 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13701690 | 0.88 | SMPD1 (0.71) | SMPD1MAOBNR4A2GPR132MEN1 | |
| SCHEMBL2089324 | 0.86 | HDAC3 (0.59) | MAOBNR4A2MEN1KMT2ANR1H4 | |
| SCHEMBL9565396 | 0.82 | LMNA (0.50) | SMPD1MEN1KMT2ANR1H4SMN1; SMN2 | |
| SCHEMBL13702365 | 0.81 | SMPD1 (0.76) | SMPD1MAOBNR4A2GPR132MEN1 | |
| SCHEMBL6301076 | 0.81 | NPC1 (0.57) | MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL27939013 | 0.81 | LMNA (0.49) | SMPD1MAOBGPR132KMT2ASMN1; SMN2 | |
| SCHEMBL21616251 | 0.80 | SMPD1 (0.74) | SMPD1MAOBNR4A2GPR132MEN1 | |
| SCHEMBL1608032 | 0.80 | SMPD1 (1.00) | SMPD1MAOBNR4A2GPR132MEN1 | |
| SCHEMBL7410475 | 0.80 | SMPD1 (0.78) | SMPD1MAOBNR4A2GPR132MEN1 | |
| SCHEMBL2759010 | 0.79 | NPC1 (0.61) | KMT2ACNR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080161331-A1 | Compounds Comprising an Oxazoline or Thiazoline Moiety, Processes for Making Them, and Their Uses | UCB PHARMA, S.A. (BE) | 2008-07-03 | — | — | US | claimed |
| US-7863450-B2 | Compounds comprising an oxazoline or thiazoline moiety, processes for making them, and their uses | UCB PHARMA, S.A. (BE) | 2011-01-04 | — | — | US | disclosed |
| US-20080161331-A1 | Compounds Comprising an Oxazoline or Thiazoline Moiety, Processes for Making Them, and Their Uses | UCB PHARMA, S.A. (BE) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161331-A1 | Compounds Comprising an Oxazoline or Thiazoline Moiety, Processes for Making Them, and Their Uses | NR1H3, NR1I3, NR1I2 | SMPD1 4763/4885MAOB 771/4885NR4A2 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.