Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6301076 | 0.86 | NPC1 (0.57) | NPC1RAB9AATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL27939013 | 0.83 | LMNA (0.49) | LMNASMPD1NPC1RAB9AATM | |
| SCHEMBL2089751 | 0.82 | SMPD1 (0.66) | SMPD1SMN1; SMN2KMT2AMEN1NR1H4 | |
| SCHEMBL2759010 | 0.81 | NPC1 (0.61) | LMNANPC1RAB9AATMMAP4K4 | |
| SCHEMBL4017067 | 0.80 | SMPD1 (0.56) | LMNASMPD1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30099037 | 0.80 | SMPD1 (0.56) | LMNASMPD1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL385706 | 0.79 | RAB9A (0.59) | SMPD1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL28294885 | 0.78 | L3MBTL1 (0.57) | LMNASMPD1MAPTALDH1A1KDM4E | |
| SCHEMBL12066298 | 0.77 | NPC1 (0.57) | LMNANPC1RAB9AATMMAP4K4 | |
| SCHEMBL1665037 | 0.77 | KMT2A (0.55) | LMNASMPD1ALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560483-A1 | 4 Benzopyl isoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-09-15 | — | — | EP | disclosed |