SCHEMBL2089753

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2093664	0.94	LMNA (0.50)	LMNASPRKDM4EALDH1A1CYP1A2
	SCHEMBL646157	0.83	LMNA (0.61)	LMNASPRKDM4EALDH1A1CYP1A2
	SCHEMBL20594360	0.81	LMNA (0.65)	LMNASPRALDH1A1CYP2C19TSHR
	SCHEMBL3584113	0.79	HRH4 (0.48)	LMNASPRHRH4
	SCHEMBL2095786	0.73	HSD11B1 (0.58)	KDM4EALDH1A1KMT2ASMN1; SMN2MEN1
	SCHEMBL15402867	0.72	LMNA (0.49)	LMNASPRKDM4EALDH1A1CYP1A2
	SCHEMBL4877455	0.72	LMNA (0.57)	LMNAKDM4EALDH1A1CYP1A2CYP2C9
	SCHEMBL3123564	0.71	SMN1; SMN2 (0.71)	LMNAALDH1A1CYP1A2CYP2C9CYP2C19
	SCHEMBL13213328	0.70	LMNA (0.65)	LMNASPRKDM4EALDH1A1CYP1A2
	SCHEMBL2094805	0.70	KMT2A (0.43)	KDM4EALDH1A1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.