Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 6/20 | 0.33 |
| ▸ | HTR2B | P41595 | 5/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.31 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.31 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.31 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.31 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.31 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.31 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.31 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.31 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20897928 | 0.98 | PRKACA (0.38) | PRKACAPRKACGPRKACBDRD2DRD3 | |
| SCHEMBL20897934 | 0.79 | HTR2C (0.43) | PNMTHRH3HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL20897971 | 0.77 | HTR2C (0.42) | PNMTHRH3HTR2CHTR2BHTR2A | |
| SCHEMBL28291353 | 0.75 | MC4R (0.31) | — | |
| SCHEMBL24265339 | 0.70 | PNMT (0.54) | DRD2DRD3PNMTHTR2CHTR2B | |
| SCHEMBL603077 | 0.67 | EPAS1 (0.36) | — | |
| SCHEMBL16812299 | 0.67 | KIF11 (0.35) | — | |
| Hydrochloric Acid SCHEMBL6392234 | 0.67 | DRD2 (0.44) | PRKACAPRKACGPRKACBDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL20897980 | 0.65 | HTR2A (0.42) | PRKACAPRKACGPRKACBDRD2DRD3 | |
| SCHEMBL22265795 | 0.64 | HRH3 (0.39) | PRKACAPRKACGPRKACBHRH3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019115709-A1 | MITOCHONDRIAL INHIBITORS FOR THE TREATMENT OF PROLIFERATION DISORDERS | Basilea Pharmaceutica International AG (CH) | 2019-06-20 | — | — | WO | disclosed |
| CN-109661392-A | For treating the mitochondrial inhibitors of proliferative disorder | 巴斯利尔药物国际股份公司 | 2019-04-19 | — | — | CN | disclosed |
| WO-2019072978-A1 | MITOCHONDRIAL INHIBITORS FOR THE TREATMENT OF PROLIFERATION DISORDERS | Basilea Pharmaceutica International AG (CH) | 2019-04-18 | — | — | WO | disclosed |