Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16375223 | 0.85 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL20898062 | 0.84 | CA12 (0.34) | DUTCA12CA1CA2CA9 | |
| SCHEMBL20897966 | 0.74 | — | — | |
| SCHEMBL6676004 | 0.74 | DUT (0.33) | DUTCA12CA1CA2CA9 | |
| SCHEMBL21355872 | 0.73 | DUT (0.31) | DUTCA12CA1CA2CA9 | |
| SCHEMBL31667292 | 0.72 | NOS2 (0.34) | — | |
| SCHEMBL31658780 | 0.72 | AR (0.34) | DUT | |
| SCHEMBL30792403 | 0.71 | CA12 (0.37) | DUTCA12CA1CA2CA9 | |
| SCHEMBL30922515 | 0.70 | DUT (0.36) | DUTCA12CA1CA2CA9 | |
| SCHEMBL26772128 | 0.70 | APLNR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019072978-A1 | MITOCHONDRIAL INHIBITORS FOR THE TREATMENT OF PROLIFERATION DISORDERS | Basilea Pharmaceutica International AG (CH) | 2019-04-18 | — | — | WO | disclosed |