SCHEMBL20901312

SCHEMBL20901312

C=N/C(=C\C=C/C)c1nc(-c2ccccn2)nc(-c2ccccn2)n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 5/20 0.47
▸ TDP1 Q9NUW8 1/20 0.47
▸ ALOX15 P16050 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ SLC2A1 P11166 1/20 0.38
▸ TP53 P04637 1/20 0.37
▸ METAP2 P50579 1/20 0.36
▸ METAP1 P53582 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ CYP1A2 P05177 2/20 0.36
▸ RAB9A P51151 3/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ GAA P10253 1/20 0.35
▸ MDM2 Q00987 1/20 0.35
▸ MAPT P10636 2/20 0.35
▸ NPSR1 Q6W5P4 2/20 0.35
▸ HTT P42858 1/20 0.35
▸ FFAR1 O14842 3/20 0.34
▸ ADORA3 P0DMS8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25493745 0.87 TP53 (0.47) KDM4ETDP1ALOX15L3MBTL1SLC2A1
SCHEMBL20169564 0.80 KDM4E (0.37) KDM4ETDP1ALDH1A1CYP1A2RAB9A
SCHEMBL22147418 0.78 CNR1 (0.37) KDM4ETDP1
SCHEMBL22650171 0.77 KDM4E (0.36) KDM4ETDP1TP53ALDH1A1RAB9A
SCHEMBL19101609 0.76 TSHR (0.32) KDM4ETDP1ALOX15L3MBTL1ALDH1A1
SCHEMBL20903539 0.76 KDM4E (0.42) KDM4ETDP1L3MBTL1TP53ALDH1A1
SCHEMBL21743331 0.73 HSP90AA1 (0.35) KDM4ETDP1ALOX15L3MBTL1SLC2A1
SCHEMBL20169567 0.72 KAT6A (0.35) KDM4ETDP1ALOX15L3MBTL1TP53
SCHEMBL24728527 0.70 L3MBTL1 (0.38) KDM4EL3MBTL1TP53ALDH1A1CYP1A2
SCHEMBL20363506 0.70 KDM4E (0.43) KDM4ETDP1ALOX15L3MBTL1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024044619-A2 METHODS OF AND DEVICES/APPARATUS FOR DETECTING, TRIGGERING, AND USING CELL-TO-CELL COMMUNICATION IMMUNOLIGHT, LLC (US) 2024-02-29 — — WO disclosed
US-11833367-B2 Methods, devices, and compositions for measuring and inducing cell-to-cell communication, and therapeutic uses thereof IMMUNOLIGHT, LLC. 2023-12-05 — — US disclosed
US-20200114164-A1 METHODS, DEVICES, AND COMPOSITIONS FOR MEASURING AND INDUCING CELL-TO-CELL COMMUNICATION, AND THERAPEUTIC USES THEREOF IMMUNOLIGHT, LLC. (US) 2020-04-16 — — US disclosed
US-10263194-B2 Light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-04-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11833367-B2 Methods, devices, and compositions for measuring and inducing cell-to-cell communication, and therapeutic uses thereof CD47, PBK, EPCAM KDM4E 4585/4885TDP1 1698/4885ALOX15 761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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