Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | METAP1 | P53582 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20901312 | 0.87 | KDM4E (0.47) | TP53KDM4ETDP1HTTALOX15 | |
| SCHEMBL19101609 | 0.76 | TSHR (0.32) | KDM4ETDP1LMNASMN1; SMN2ALOX15 | |
| SCHEMBL24565502 | 0.76 | TP53 (0.55) | TP53KDM4ETDP1LMNASMN1; SMN2 | |
| SCHEMBL20903539 | 0.76 | KDM4E (0.42) | TP53KDM4ETDP1LMNASMN1; SMN2 | |
| SCHEMBL20169564 | 0.75 | KDM4E (0.37) | KDM4ETDP1LMNASMN1; SMN2HTT | |
| SCHEMBL21128809 | 0.75 | TP53 (0.49) | TP53KDM4ETDP1LMNASMN1; SMN2 | |
| SCHEMBL22147418 | 0.73 | CNR1 (0.37) | KDM4ETDP1 | |
| SCHEMBL22650171 | 0.72 | KDM4E (0.36) | TP53KDM4ETDP1LMNASMN1; SMN2 | |
| SCHEMBL21098282 | 0.72 | TP53 (0.49) | TP53KDM4ETDP1LMNASMN1; SMN2 | |
| SCHEMBL21743331 | 0.71 | HSP90AA1 (0.35) | TP53KDM4ETDP1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3597696-B1 | RUBBER COMPOSITION FOR TIRES AND PNEUMATIC TIRE | SUMITOMO RUBBER IND (JP) | 2023-05-17 | — | — | EP | disclosed |