SCHEMBL20902005

SCHEMBL20902005

COc1ccccc1-n1ccc(OCc2c(C)cccc2N(C)N)n1

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.33
HTR7 P34969 3/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
ATP4A P20648 3/20 0.33
ATP4B P51164 3/20 0.33
HTR1A P08908 3/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
SYK P43405 1/20 0.32
SLC22A12 Q96S37 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
ADORA1 P30542 1/20 0.31
DRD2 P14416 1/20 0.31
HTR6 P50406 1/20 0.31
USP2 O75604 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22564025 0.91 ALDH1A1 (0.35) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL22563777 0.90 CYP1A2 (0.32) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL22564364 0.86 KMT2A (0.34) HTR7ATP4AATP4BMEN1KMT2A
SCHEMBL22564407 0.85 NR1H4 (0.33) MEN1KMT2A
SCHEMBL20844971 0.81 EDNRA (0.30)
SCHEMBL22563890 0.81 GPBAR1 (0.33) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL22564045 0.81 SIGMAR1 (0.33) HTR7CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL22563768 0.80 CYP1A2 (0.31) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL22564406 0.80 MEN1 (0.33) MEN1KMT2A
SCHEMBL22563981 0.79 SIGMAR1 (0.41) CYP1A2CYP3A4CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3025586-B1 PLANT DISEASE CONTROL COMPOSITION AND ITS USE SUMITOMO CHEMICAL CO (JP) 2019-04-17 EP disclosed