SCHEMBL22563777

SCHEMBL22563777

Cc1cccc(N(C)N)c1COc1ccn(-c2ccccc2OC(C)C)n1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
NISCH Q9Y2I1 1/20 0.31
NR1H4 Q96RI1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20902005 0.90 HTR2A (0.33) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL22564025 0.89 ALDH1A1 (0.35) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL22563890 0.79 GPBAR1 (0.33) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL22564407 0.79 NR1H4 (0.33) NR1H4
SCHEMBL22564045 0.79 SIGMAR1 (0.33) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL22563768 0.78 CYP1A2 (0.31) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL22564406 0.78 MEN1 (0.33)
SCHEMBL22563981 0.77 SIGMAR1 (0.41) CYP1A2CYP3A4CYP2D6CYP2C19NR1H4
SCHEMBL16467783 0.77 NR1H4 (0.32) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL20845279 0.77 GRM5 (0.32) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed