Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | CCR8 | P51685 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21032002 | 0.81 | CCR1 (0.64) | CCR1CCR8NPC1PDGFRBKDR | |
| SCHEMBL21031257 | 0.79 | CCR1 (0.60) | CCR1CCR8NPC1TOP1CCR5 | |
| SCHEMBL127144 | 0.78 | TOP1 (0.49) | CCR1CCR8NPC1RAB9ATOP1 | |
| SCHEMBL8654916 | 0.78 | CCR1 (0.61) | CCR1CCR8NPC1SMN1; SMN2KDM4E | |
| SCHEMBL669488 | 0.77 | LMNA (0.61) | CCR1CCR8NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12655491 | 0.77 | TOP1 (0.47) | NPC1RAB9ATOP1L3MBTL1MEN1 | |
| SCHEMBL15998544 | 0.75 | TOP1 (0.46) | NPC1RAB9ATOP1MEN1KMT2A | |
| SCHEMBL27820373 | 0.75 | LMNA (0.57) | CCR1CCR8NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12315219 | 0.74 | ALDH1A1 (0.56) | NPC1PDGFRBKDRFLT3RAB9A | |
| SCHEMBL16678847 | 0.74 | ALDH1A1 (0.49) | RAB9ASMN1; SMN2KDM4EL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3470494-A1 | OLED COMPRISING ORGANIC COMPOUNDS CONTAINING B-N HETEROCYCLES | Universal Display Corporation (US) | 2019-04-17 | — | — | EP | disclosed |