SCHEMBL127144

SCHEMBL127144

c1ccc(-c2ccc3c4cccnc4c4ncccc4c3n2)cc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TOP1 P11387 4/20 0.49
NPC1 O15118 3/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
HSP90AA1 P07900 2/20 0.44
MEN1 O00255 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43
ALDH1A1 P00352 1/20 0.43
AURKA O14965 1/20 0.43
PRKACA P17612 1/20 0.43
ADORA2A P29274 1/20 0.43
LIMK1 P53667 1/20 0.41
CCR1 P32246 3/20 0.41
CCR8 P51685 3/20 0.41
MKNK2 Q9HBH9 1/20 0.40
CCR5 P51681 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12655491 0.95 TOP1 (0.47) TOP1NPC1L3MBTL1HSP90AA1MEN1
SCHEMBL15998544 0.93 TOP1 (0.46) TOP1NPC1HSP90AA1MEN1RAB9A
SCHEMBL14884117 0.89 KMT2A (0.44) TOP1L3MBTL1HSP90AA1MEN1KMT2A
SCHEMBL19335781 0.86 MEN1 (0.52) L3MBTL1HSP90AA1MEN1RAB9AKMT2A
SCHEMBL20149675 0.85 MAPT (0.44) TOP1NPC1HSP90AA1MEN1RAB9A
SCHEMBL29340578 0.84 L3MBTL1 (0.58) TOP1NPC1L3MBTL1HSP90AA1CCR1
SCHEMBL29340576 0.84 L3MBTL1 (0.58) TOP1NPC1L3MBTL1HSP90AA1CCR1
SCHEMBL29340580 0.84 L3MBTL1 (0.58) TOP1NPC1L3MBTL1HSP90AA1CCR1
SCHEMBL15761437 0.84 TOP1 (0.39) TOP1NPC1L3MBTL1HSP90AA1ALDH1A1
SCHEMBL26352188 0.83 TOP1 (0.39) TOP1NPC1HSP90AA1MEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1946 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12048237-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-23 US disclosed
US-20240244955-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-18 US disclosed
EP-3816175-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2024-07-17 EP disclosed
EP-4401530-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2024-07-17 EP disclosed
US-12041846-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-16 US disclosed
US-12041846-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-16 US disclosed
US-12035618-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
US-12035618-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
US-20240218004-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20100187984-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED UNIVERSAL DISPLAY CORPORATION (US) 2010-07-29 US disclosed
US-20100187984-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED UNIVERSAL DISPLAY CORPORATION (US) 2010-07-29 US disclosed
US-20100141127-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2010-06-10 US disclosed
US-20100141127-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2010-06-10 US disclosed
WO-2010036765-A1 ORGANOSELENIUM MATERIALS AND THEIR USES IN ORGANIC LIGHT EMITTING DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2010-04-01 WO disclosed
US-20100072887-A1 ORGANOSELENIUM MATERIALS AND THEIR USES IN ORGANIC LIGHT EMITTING DEVICES UNIVERSAL DISPLAY CORPORATION 2010-03-25 US disclosed
US-20100072887-A1 ORGANOSELENIUM MATERIALS AND THEIR USES IN ORGANIC LIGHT EMITTING DEVICES UNIVERSAL DISPLAY CORPORATION 2010-03-25 US disclosed
US-20090115316-A1 ORGANIC ELECTROLUMINESCENT DEVICE HAVING AN AZATRIPHENYLENE DERIVATIVE GLOBAL OLED TECHNOLOGY LLC 2009-05-07 US disclosed
US-20090115316-A1 ORGANIC ELECTROLUMINESCENT DEVICE HAVING AN AZATRIPHENYLENE DERIVATIVE GLOBAL OLED TECHNOLOGY LLC 2009-05-07 US disclosed
US-20090115316-A1 ORGANIC ELECTROLUMINESCENT DEVICE HAVING AN AZATRIPHENYLENE DERIVATIVE GLOBAL OLED TECHNOLOGY LLC 2009-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12035618-B2 Electroluminescent devices ELAVL1, ELAVL3, JUND TOP1 1712/4885NPC1 1484/4885L3MBTL1 440/4885
US-20100141127-A1 PHOSPHORESCENT EMITTERS PAICS, TYMP, NUDT1 TOP1 2121/4885NPC1 4161/4885L3MBTL1 930/4885
US-20240244955-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES AOX1, SBDS, OCIAD2 TOP1 4126/4885NPC1 2114/4885L3MBTL1 826/4885
US-20090115316-A1 ORGANIC ELECTROLUMINESCENT DEVICE HAVING AN AZATRIPHENYLENE DERIVATIVE DNMT1, EED, ALKBH2 TOP1 1827/4885NPC1 3229/4885L3MBTL1 494/4885
US-12041846-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 TOP1 2495/4885NPC1 105/4885L3MBTL1 2096/4885
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG TOP1 4649/4885NPC1 1965/4885L3MBTL1 822/4885
US-12048237-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OSBP TOP1 2995/4885NPC1 469/4885L3MBTL1 1147/4885
US-20100072887-A1 ORGANOSELENIUM MATERIALS AND THEIR USES IN ORGANIC LIGHT EMITTING DEVICES SCLY, BZW2, GPX4 TOP1 3931/4885NPC1 2971/4885L3MBTL1 843/4885
US-20100187984-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED DDT, FZD7, BRD7 TOP1 837/4885NPC1 4798/4885L3MBTL1 635/4885
US-20240218004-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, CCND2 TOP1 4038/4885NPC1 2560/4885L3MBTL1 1428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.