⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21993159 | 0.84 | — | — | |
| SCHEMBL25854527 | 0.76 | GAA (0.34) | — | |
| SCHEMBL25855355 | 0.76 | GAA (0.34) | — | |
| SCHEMBL21993160 | 0.76 | GAA (0.34) | — | |
| SCHEMBL24399512 | 0.73 | NOS1 (0.45) | — | |
| SCHEMBL21993157 | 0.71 | — | — | |
| SCHEMBL24499792 | 0.70 | CNR1 (0.33) | — | |
| SCHEMBL20904179 | 0.69 | — | — | |
| SCHEMBL2600726 | 0.66 | NOS1 (0.44) | — | |
| SCHEMBL10252488 | 0.65 | GAA (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200148652-A1 | Aminothiazole Derivatives Useful As Antiviral Agents | INNOVATIVE MOLECULES GMBH (DE) | 2020-05-14 | — | — | US | disclosed |
| US-10590094-B2 | Aminothiazole derivatives useful as antiviral agents | INNOVATIVE MOLECULES GMBH (DE) | 2020-03-17 | — | — | US | disclosed |
| US-20190112285-A1 | Aminothiazole Derivatives Useful As Antiviral Agents | INNOVATIVE MOLECULES GMBH (DE) | 2019-04-18 | — | — | US | disclosed |