SCHEMBL25855355

SCHEMBL25855355

Cc1nc(C)c([S@@](C)(=N)=O)s1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.34
KIT P10721 1/20 0.32
LMNA P02545 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
CHRM5 P08912 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.30
THRB P10828 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25854527 1.00 GAA (0.34) GAAKITLMNASMN1; SMN2TDP1
SCHEMBL21993160 1.00 GAA (0.34) GAAKITLMNASMN1; SMN2TDP1
SCHEMBL1640359 0.82 ALDH1A1 (0.34) GAAKITLMNACHRM5ALDH1A1
SCHEMBL22002811 0.81 GAA (0.33) GAAKITLMNASMN1; SMN2TDP1
SCHEMBL24399512 0.79 NOS1 (0.45) GAALMNASMN1; SMN2TDP1ALDH1A1
SCHEMBL50995 0.77 CA12 (0.40) GAAKITLMNACHRM5TP53
SCHEMBL20904183 0.76
SCHEMBL24499792 0.76 CNR1 (0.33)
SCHEMBL4902068 0.76 TP53 (0.34) GAAKITSMN1; SMN2CHRM5ALDH1A1
SCHEMBL21993158 0.75 CHRM5 (0.35) GAACHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4209491-A1 ENANTIOMERS OF SUBSTITUTED THIAZOLES AS ANTIVIRAL COMPOUNDS Innovative Molecules GmbH (DE) 2023-07-12 EP disclosed