SCHEMBL2600726

SCHEMBL2600726

Cc1nc(C(C)C)sc1C

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 1/20 0.44
CTSA P10619 1/20 0.34
APLNR P35414 3/20 0.33
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
TLR8 Q9NR97 1/20 0.30
TLR7 Q9NYK1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20738686 0.80 NOS1 (0.41) NOS1CTSAAPLNRALDH1A1GAA
SCHEMBL11458946 0.80 NOS1 (0.41) NOS1CTSAAPLNRALDH1A1GAA
SCHEMBL3248176 0.80 NOS1 (0.46) NOS1CTSAAPLNRALDH1A1GAA
SCHEMBL6010207 0.80 NOS1 (0.41) NOS1CTSAAPLNRALDH1A1GAA
SCHEMBL30209038 0.80 NOS1 (0.46) NOS1CTSAAPLNRALDH1A1GAA
SCHEMBL23869812 0.80 NOS1 (0.41) NOS1CTSAAPLNRALDH1A1GAA
SCHEMBL12179230 0.80 NOS1 (0.41) NOS1CTSAAPLNRALDH1A1GAA
SCHEMBL14226108 0.77 TLR8 (0.33) TLR8TLR7
SCHEMBL29271546 0.77 NOS1 (0.43) NOS1CTSAAPLNR
SCHEMBL12848866 0.77 NOS1 (0.38) NOS1CTSAAPLNRTLR8TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116814525-B Culture medium for culturing Babylonia embryos and method for culturing Babylonia embryos outside capsules 广东海洋大学 2024-04-30 CN claimed
CN-117223657-B Method for cultivating low-salt-resistant long-speed and fast Babylonia 广东海洋大学 2024-04-05 CN claimed
CN-114903128-B Crayfish compound feed and preparation method thereof 湖南文和友乔口小龙虾养殖有限公司 2024-01-16 CN claimed
CN-117223657-A Method for cultivating low-salt-resistant long-speed and fast Babylonia 广东海洋大学 2023-12-15 CN claimed
CN-116814525-A Culture medium for culturing Babylonia embryos and method for culturing Babylonia embryos outside capsules 广东海洋大学 2023-09-29 CN claimed
CN-116218427-A Acrylic ester adhesive and preparation method and application thereof 华东理工大学 2023-06-06 CN claimed
US-20240199604-A1 SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-06-20 US disclosed
CN-116814525-B Culture medium for culturing Babylonia embryos and method for culturing Babylonia embryos outside capsules 广东海洋大学 2024-04-30 CN disclosed
CN-116814525-B Culture medium for culturing Babylonia embryos and method for culturing Babylonia embryos outside capsules 广东海洋大学 2024-04-30 CN disclosed
CN-117223657-B Method for cultivating low-salt-resistant long-speed and fast Babylonia 广东海洋大学 2024-04-05 CN disclosed
CN-117084204-B Buffer solution for improving hatching rate and survival rate of eastern conch oocysts and method for hatching eastern conch oocysts 广东海洋大学 2024-04-05 CN disclosed
CN-114903128-B Crayfish compound feed and preparation method thereof 湖南文和友乔口小龙虾养殖有限公司 2024-01-16 CN disclosed
CN-117223657-A Method for cultivating low-salt-resistant long-speed and fast Babylonia 广东海洋大学 2023-12-15 CN disclosed
US-20080015195-A1 Novel Heteroaromatic Inhibitors of Fructose-1,6-Bisphosphatase METABASIS THERAPEUTICS, INC. (US) 2008-01-17 US disclosed
US-7312219-B2 Heteroaromatic inhibitors of fructose 1,6-bisphosphatase METABASIS THERAPEUTICS, INC. (US) 2007-12-25 US disclosed
US-20070244096-A1 Fused Bicyclic Nitrogen-Containing Heterocycles JAPAN TOBACCO INC. (JP) 2007-10-18 US disclosed
US-20070232571-A1 Novel Heteroaromatic Inhibitors of Fructose-1,6-Bisphosphatase METABASIS THERAPEUTICS, INC. (US) 2007-10-04 US disclosed
US-7244727-B2 Fused bicyclic nitrogen-containing heterocycles JAPAN TOBACCO INC. (JP) 2007-07-17 US disclosed
US-20070135467-A1 HETEROCYCLIC CETP INHIBITORS BRISTOL-MYERS SQUIBB COMPANY 2007-06-14 US disclosed
US-6579553-B1 Reaction product cysteine, hydrogen sulfide, ammonium sulfide and extracellular liquid fusarium extracts used as food flavors ZENECA LIMITED (GB) 2003-06-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199604-A1 SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS MAPT, HTT, PSEN1 NOS1 4315/4885CTSA 1917/4885APLNR 528/4885
US-20080015195-A1 Novel Heteroaromatic Inhibitors of Fructose-1,6-Bisphosphatase FBP1, ALDOA, G6PC1 NOS1 3032/4885CTSA 2347/4885APLNR 4322/4885
US-20070135467-A1 HETEROCYCLIC CETP INHIBITORS CETP, CES1, NPC1 NOS1 3695/4885CTSA 348/4885APLNR 4348/4885
US-20070244096-A1 Fused Bicyclic Nitrogen-Containing Heterocycles PC, HCCS, MYC NOS1 833/4885CTSA 1117/4885APLNR 1068/4885
US-20070232571-A1 Novel Heteroaromatic Inhibitors of Fructose-1,6-Bisphosphatase FBP1, ALDOA, G6PC1 NOS1 3032/4885CTSA 2347/4885APLNR 4322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.