SCHEMBL2090427

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4002789	0.89	ALDH1A1 (0.46)	ALDH1A1CA12CA1CA2CA7
	SCHEMBL7952922	0.80	ALDH1A1 (0.46)	ALDH1A1CA12CA1CA2CA7
	SCHEMBL5185794	0.78	ALDH1A1 (0.48)	ALDH1A1CA12CA1CA2CA7
	SCHEMBL7952918	0.77	ALDH1A1 (0.42)	ALDH1A1CA12CA1CA2CA7
	SCHEMBL6549241	0.77	IDO1 (0.53)	ALDH1A1CA12CA1CA2CA7
	SCHEMBL18536034	0.76	MAPK1 (0.46)	CA12CA1CA2CA7CA9
	SCHEMBL21119156	0.76	PTPN1 (0.37)	CA12CA1CA2CA7CA9
	SCHEMBL2096172	0.75	ALDH1A1 (0.50)	ALDH1A1CA12CA1CA2CA7
	SCHEMBL27602227	0.74	ALDH1A1 (0.50)	ALDH1A1MAPK1CALM1
	SCHEMBL8009626	0.74	CYP1A2 (0.44)	ALDH1A1CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.